Center for Musculoskeletal Surgery, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany.
Sci Rep. 2023 Feb 14;13(1):2589. doi: 10.1038/s41598-023-29545-5.
Restricted spinopelvic mobility received attention as a contributing factor for total hip arthroplasty (THA) instability. However, it is still unknown, how the spinopelvic function is influenced by age. In identifying the patients at highest risk for altered spinopelvic mechanics the study aimed to determine the association of age on the individual segments of the spinopelvic complex and global spinal sagittal alignment in patients undergoing THA. 197 patients were included in the prospective observational study conducting biplanar stereoradiography (EOS) in standing and sitting position pre-and postoperatively. Two independent investigators assessed C7-sagittal vertical axis (C7-SVA), cervical lordosis (CL), thoracic kyphosis (TK), lumbar lordosis (LL), pelvic incidence (PI), sacral slope (SS), anterior plane pelvic tilt (APPT), and pelvic femoral angle (PFA). Key segments of the spinopelvic complex are defined as lumbar flexibility (∆ LL = LL - LL), pelvic mobility (∆ SS = SS - SS) and hip motion (∆ PFA = PFA - PFA). Pelvic mobility was further defined based on ∆ SS = SS - SS as stiff (∆ SS < 10°), normal (∆ SS ≥ 10°-30°) and hypermobile (∆ SS > 30°). The patient collective was classified into three groups: (1) < 60 years (n = 56), (2) ≥ 60-79 years (n = 112) and (3) ≥ 80 years (n = 29). Lumbar flexibility (∆ LL) was decreased with increasing age between all groups (36.1° vs. 23.1° vs. 17.2°/p < 0.000, p = 0.020, p < 0.000) postoperatively. Pelvic mobility (∆ SS) was decreased in the groups 2 and 3 compared to group 1 (21.0° and 17.9° vs. 27.8°/p < 0.000, p = 0.371, p = 0.001). Pelvic retroversion in standing position (APPT) was higher in group 2 and 3 compared to group 1 (1.9° and - 0.5° vs 6.9°/p < 0.000, p = 0.330, p < 0.000). Global sagittal spinal balance (C7-SVA) showed more imbalance in groups 2 and 3 compared to group 1 (60.4 mm and 71.2 mm vs. 34.5 mm/p < 0.000, p = 0.376, p < 0.000) postoperatively. The preoperative proportion of patients with stiff pelvic mobility in group 1 was distinctly lower than in group 3 (23.2% vs. 35.7%) and declined in group 1 to 1.8% compared to 20.7% in group 3 after THA. Changes after THA were reported for groups 1 and 2 representing spinopelvic complex key parameter lumbar flexibility (∆ LL), pelvic mobility (∆ SS) and hip motion (∆ PFA), but not for group 3. This is the first study to present age-adjusted normative values for spinopelvic mobility. The subgroups with increased age were identified as risk cohort for altered spinopelvic mechanics and enhanced sagittal spinal imbalance and limited capacity for improvement of mobility after THA. This valuable information serves to focus in the preoperative screening on the THA candidates with the highest risk for abnormal spinopelvic function.
脊柱骨盆活动受限被认为是全髋关节置换术(THA)不稳定的一个致病因素。然而,目前尚不清楚年龄是如何影响脊柱骨盆功能的。本研究旨在确定年龄与接受 THA 患者脊柱骨盆复合体各个节段和整体脊柱矢状面排列的相关性,以确定哪些患者的脊柱骨盆力学改变风险最高。197 名患者前瞻性地参与了这项研究,他们在术前和术后接受了双平面立体射线照相术(EOS)的站立和坐姿检查。两名独立的研究者评估了 C7 矢状垂直轴(C7-SVA)、颈椎前凸(CL)、胸椎后凸(TK)、腰椎前凸(LL)、骨盆入射角(PI)、骶骨倾斜角(SS)、前平面骨盆倾斜角(APPT)和骨盆股骨角(PFA)。脊柱骨盆复合体的关键节段被定义为腰椎活动度(∆ LL=LL-LL)、骨盆活动度(∆ SS=SS-SS)和髋关节运动(∆ PFA=PFA-PFA)。进一步根据 ∆ SS=SS-SS 将骨盆活动度定义为僵硬(∆ SS<10°)、正常(∆ SS≥10°-30°)和过度活动(∆ SS>30°)。患者群体分为三组:(1)<60 岁(n=56),(2)≥60-79 岁(n=112)和(3)≥80 岁(n=29)。三组患者术后腰椎活动度(∆ LL)均随年龄增长而降低(36.1° vs. 23.1° vs. 17.2°/p<0.000,p=0.020,p<0.000)。与组 1 相比,组 2 和组 3 的骨盆活动度(∆ SS)降低(21.0°和 17.9° vs. 27.8°/p<0.000,p=0.371,p=0.001)。与组 1 相比,组 2 和组 3 在站立位时骨盆后倾(APPT)更高(1.9°和-0.5° vs 6.9°/p<0.000,p=0.330,p<0.000)。与组 1 相比,组 2 和组 3 的术后整体脊柱矢状平衡(C7-SVA)更加失衡(60.4mm 和 71.2mm vs. 34.5mm/p<0.000,p=0.376,p<0.000)。与组 3 相比,组 1 术前僵硬性骨盆活动度患者的比例明显较低(23.2% vs. 35.7%),THA 后组 1 下降至 1.8%,而组 3 下降至 20.7%。第 1 组和第 2 组报告了 THA 后的变化,代表脊柱骨盆复合体的关键参数腰椎活动度(∆ LL)、骨盆活动度(∆ SS)和髋关节运动(∆ PFA),但第 3 组没有。这是第一项提出脊柱骨盆活动度年龄调整正常范围的研究。年龄较大的亚组被确定为脊柱骨盆力学改变和矢状面脊柱失衡风险增加的风险队列,并且在 THA 后改善活动度的能力有限。这些有价值的信息有助于在术前筛选中关注具有异常脊柱骨盆功能风险最高的 THA 候选者。