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关节镜肩关节手术后的静脉血栓栓塞症:系统评价。

Venous thromboembolism after arthroscopic shoulder surgery: a systematic review.

机构信息

Department of Orthopedics, Orthopedic Research Institute, West China Hospital, Sichuan University, No. 37, Guoxue Road, Wuhou District, Chengdu, 610041, Sichuan Province, People's Republic of China.

West China School of Medicine, Sichuan University, Chengdu, People's Republic of China.

出版信息

J Orthop Surg Res. 2023 Feb 14;18(1):103. doi: 10.1186/s13018-023-03592-0.

Abstract

PURPOSE

To summarize the incidence, risk factors, diagnosis methods, prophylaxis methods, and treatment of venous thromboembolism (VTE) following arthroscopic shoulder surgery.

METHODS

Literature on VTE after arthroscopic shoulder surgeries was summarized, and all primary full-text articles reporting at least 1 case of deep vein thrombosis (DVT) or pulmonary embolism (PE) after arthroscopic shoulder surgeries were included. Articles were critically appraised and systematically analyzed to determine the incidence, risk factors, diagnosis, prophylaxis, and management of VTE following arthroscopic shoulder surgeries.

RESULTS

This study included 42 articles in which the incidence of VTE ranges from 0 to 5.71% and the overall incidence was 0.26%. Most VTE events took place between the operation day and the 14th day after the operation (35/51). Possible risk factors included advanced age (> 70 years), obesity (BMI ≥ 30 kg/m), diabetes mellitus, thrombophilia, history of VTE, prolonged operation time, hormone use, and immobilization after surgery. The most common prophylaxis method was mechanical prophylaxis (13/15). No statistical difference was detected when chemoprophylaxis was applied. The management included heparinization followed by oral warfarin, warfarin alone and rivaroxaban, a direct oral anticoagulant.

CONCLUSION

Based on the included studies, the incidence rate of VTE after arthroscopic shoulder surgeries is relatively low. The risk factors for VTE are still unclear. CT/CTA and ultrasound were the mainstream diagnosis methods for PE and DVT, respectively. Current evidence shows that chemical prophylaxis did not deliver significant benefits, since none of the existing studies reported statistically different results. High-quality studies focusing on the prophylaxis and management of VTE population undergoing arthroscopic shoulder surgeries should be done in the future.

摘要

目的

总结关节镜肩关节手术后静脉血栓栓塞症(VTE)的发生率、危险因素、诊断方法、预防方法和治疗方法。

方法

总结了关节镜肩关节手术后 VTE 的文献,并纳入了所有报告至少 1 例关节镜肩关节手术后深静脉血栓形成(DVT)或肺栓塞(PE)的原始全文文章。对文章进行了批判性评价和系统分析,以确定关节镜肩关节手术后 VTE 的发生率、危险因素、诊断、预防和治疗。

结果

本研究共纳入 42 篇文章,VTE 的发生率为 0 至 5.71%,总发生率为 0.26%。大多数 VTE 事件发生在手术当天至术后第 14 天(35/51)。可能的危险因素包括年龄较大(>70 岁)、肥胖(BMI≥30kg/m)、糖尿病、血栓形成倾向、VTE 病史、手术时间延长、激素使用和术后固定。最常见的预防方法是机械预防(13/15)。应用化学预防时未检测到统计学差异。管理方法包括肝素化后口服华法林、华法林单独使用和利伐沙班,一种直接口服抗凝剂。

结论

根据纳入的研究,关节镜肩关节手术后 VTE 的发生率相对较低。VTE 的危险因素仍不清楚。CT/CTA 和超声分别是 PE 和 DVT 的主流诊断方法。目前的证据表明,化学预防并没有带来显著的益处,因为现有的研究都没有报告统计学上的差异结果。未来应开展针对行关节镜肩关节手术的 VTE 人群进行预防和管理的高质量研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14ff/9930260/f8add2c0f81d/13018_2023_3592_Fig1_HTML.jpg

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