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单发髓外浆细胞瘤的 CT 和 MRI 表现:十例病例报告及文献复习。

CT and MRI Findings of Solitary Extramedullary Plasmacytoma: A Series of Ten Case Reports and Review of Literature.

机构信息

Department of Radiology, Affiliated Hospital of Guilin Medical University, NO.12 Lequn Road, Xiufeng District, Guilin City, Guangxi 541001, People's Republic of China.

Department of Radiology, The First Affiliated Hospital of Guangxi Medical University, Nanning City, Guangxi 530021, People's Republic of China.

出版信息

Curr Med Imaging. 2023;19(11):1308-1314. doi: 10.2174/1573405619666230213114231.

DOI:10.2174/1573405619666230213114231
PMID:36788682
Abstract

OBJECTIVE

The study aimed to analyze computed tomography and magnetic resonance imaging features of patients with solitary extramedullary plasmacytoma.

METHODS

Ten cases with solitary extramedullary plasmacytoma were included in this study. CT and MRI features of solitary extramedullary plasmacytoma were retrospectively analyzed.

RESULTS

This study included both males (n = 8) and females (n = 2), with a median age of 48 (range 21-72 years old). The organs or anatomical structures involved were nasopharynx (n = 3), orbit (n = 1), left tentorium (n = 1), nasal cavity and meatus (n = 2), small intestine and mesentery (n = 1), as well as posterior thoracic wall (n = 2). The median maximum diameter of the tumors was 3.2 cm (range 0.8- 15.2 cm). The tumor shapes were round (n = 7), stripped (n = 1), irregular (n = 1), and nodular (n = 1). The margin of the tumors was well-defined (n = 7) and partially well-defined (n = 3). There were 3 cases with bone destruction and 1 with a tissue invasion adjacent to the tumor, calcification (n = 1), and cystic degeneration (n = 2). Enlarged tumoral vessels (n = 4) could also be observed. The CT attenuation and MR signal intensity of tumors were heterogeneous (n = 4) and homogenous (n = 6). After the injection of the contrast agent, marked (n = 5), mild (n = 1), mild to moderate (n = 1), and delayed enhancement (n = 1) could be observed.

CONCLUSION

A well-defined homogeneous solitary mass occurring at the head and neck with a marked enhancement, an adjacent tissue invasion, enlarged tumoral vessels, and bone destruction can indicate the diagnosis of solitary extramedullary plasmacytoma.

摘要

目的

本研究旨在分析单发髓外浆细胞瘤患者的计算机断层扫描(CT)和磁共振成像(MRI)特征。

方法

本研究纳入 10 例单发髓外浆细胞瘤患者。回顾性分析单发髓外浆细胞瘤的 CT 和 MRI 特征。

结果

本研究包括男性 8 例,女性 2 例,中位年龄 48 岁(范围 21-72 岁)。累及的器官或解剖结构包括鼻咽(n=3)、眼眶(n=1)、左天幕(n=1)、鼻腔和鼻道(n=2)、小肠和肠系膜(n=1)、后胸壁(n=2)。肿瘤最大直径中位数为 3.2cm(范围 0.8-15.2cm)。肿瘤形状为圆形(n=7)、条状(n=1)、不规则形(n=1)和结节状(n=1)。肿瘤边缘清楚(n=7)和部分清楚(n=3)。有 3 例伴有骨破坏,1 例伴有肿瘤邻近组织侵犯,1 例伴钙化,2 例伴囊变。还可观察到增大的肿瘤血管(n=4)。肿瘤 CT 密度和 MRI 信号强度不均匀(n=4)和均匀(n=6)。注射造影剂后,可见明显(n=5)、轻度(n=1)、轻度至中度(n=1)和延迟强化(n=1)。

结论

发生于头颈部、边界清楚、均匀的单发肿块,伴有明显强化、邻近组织侵犯、增大的肿瘤血管和骨破坏,可提示单发髓外浆细胞瘤的诊断。

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