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尽管“哨兵”桡骨远端骨折后 DEXA 筛查有所增加,但抗骨质疏松治疗的趋势仍在下降。

Declining Trend in Anti-osteoporotic Treatment, Despite a Rise in DEXA Screening Following "Sentinel" Distal Radius Fractures.

机构信息

The Ohio State University Wexner Medical Center, Columbus, USA.

出版信息

Hand (N Y). 2024 Sep;19(6):978-985. doi: 10.1177/15589447231153176. Epub 2023 Feb 14.

Abstract

PURPOSE

To understand national trends and costs associated with the utilization of anti-osteoporotic medication and DEXA screening within the year following a sentinel/primary distal radius fracture.

METHODS

The 2008-2015Q1 Humana Administrative Claims database was queried to identify patients aged ≥50 years, with a "sentinel" occurrence of a primary closed distal radius fracture. Linear regression models were used to report and assess for significant trends in utilization of anti-osteoporotic medication and DEXA screenings within the year following the fracture. Multivariate logistic regression analyses were used to assess for factors associated with receiving or not receiving anti-osteoporotic medication.

RESULTS

A total of 14 526 sentinel distal radius fractures were included in the study. Only 7.2% (n = 1046) of patients received anti-osteoporosis medication in the year following the distal radius fracture. Treatment with medication for osteoporosis declined from 8.2% in 2008 to 5.9% in 2015, whereas the rate of DEXA screening increased from 14.8% in 2008 to 23.6% in 2015. The most common prescribed treatment was alendronate sodium (n = 835; 79.8%-$49/patient). Factors associated with increased odds of receiving anti-osteoporotic medication were age 70 to 79 years (odds ratio [OR], 1.45; = .014), age 80 to 89 years (OR, 1.66; = .001), Asian (OR, 2.95; = .002) or Hispanic (OR, 1.77; = .006) ethnicity, belonging to South (OR, 1.19; = .029) or West (OR, 1.37; = .010), and having an Elixhauser Comorbidity Index score of 3 (OR, 2.14; = .024) or > 3 (OR, 2.05; = .022).

CONCLUSIONS

Despite a rising utilization of DEXA screening following "sentinel" distal radius fractures, the proportion of individuals who receive anti-osteoporotic treatment is decreasing over time.

摘要

目的

了解在哨兵/原发性桡骨远端骨折后一年内使用抗骨质疏松药物和 DEXA 筛查的国家趋势和成本。

方法

使用 2008-2015Q1Humana 行政索赔数据库,确定年龄≥50 岁的患者,具有“哨兵”原发性闭合性桡骨远端骨折的发生。线性回归模型用于报告和评估骨折后一年内使用抗骨质疏松药物和 DEXA 筛查的显著趋势。使用多变量逻辑回归分析评估与接受或不接受抗骨质疏松药物治疗相关的因素。

结果

研究共纳入 14526 例哨兵桡骨远端骨折。仅有 7.2%(n=1046)的患者在桡骨远端骨折后一年内接受抗骨质疏松药物治疗。骨质疏松症药物治疗的比例从 2008 年的 8.2%下降到 2015 年的 5.9%,而 DEXA 筛查的比例从 2008 年的 14.8%上升到 2015 年的 23.6%。最常见的处方治疗是阿仑膦酸钠(n=835;79.8%,$49/患者)。与增加接受抗骨质疏松药物治疗的几率相关的因素包括 70-79 岁(比值比[OR],1.45;.014)、80-89 岁(OR,1.66;.001)、亚洲(OR,2.95;.002)或西班牙裔(OR,1.77;.006)种族、属于南部(OR,1.19;.029)或西部(OR,1.37;.010),以及 Elixhauser 合并症指数评分为 3(OR,2.14;.024)或>3(OR,2.05;.022)。

结论

尽管 DEXA 筛查在“哨兵”桡骨远端骨折后的应用不断增加,但接受抗骨质疏松治疗的个体比例随着时间的推移呈下降趋势。

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