Blagova Bistra, Malinova Lina, Ivanova Vesela
Maxillofacial Surgery Division, University Multiprofile Hospital for Active Treatment and Emergency Medicine "N. I. Pirogov", Gen. Totleben Blvd. 21, 1606 SofiaBulgaria.
Department of Anatomy, histology and embryology, Medical University of Sofia, 2 Zdrave Str.,1431 SofiaBulgaria.
J Oral Maxillofac Res. 2022 Dec 31;13(4):e4. doi: 10.5037/jomr.2022.13404. eCollection 2022 Oct-Dec.
Epidermoid cysts are benign lesions that occur throughout the body. Their development in the oral cavity is extremely rare. Intraosseous epidermoid cysts of the jaw are even rarer and difficult to distinguish from other lesions. For this reason, we would like to draw the attention of practitioners to this pathology as a differential diagnosis through the presented clinical case.
This study presents an unusual case of a type of epidermoid cyst in an edentulous maxilla. A 70-year-old man was referred to the Maxillofacial Surgery Division at the University Multiprofile Hospital for Active Treatment and Emergency Medicine "N. I. Pirogov", Sofia, Bulgaria, for a single radiolucent area in his anterior maxilla. The patient underwent surgery to extract the cyst.
Based on the clinical and radiographic evaluation, a preliminary diagnosis of dentigerous residual cyst was made. The histopathological examination of the hematoxylin and eosin stained sections revealed an epidermoid cyst based on the observed thick keratin layer resembling epidermis together with the stratified squamous epithelium lining with many layers of sheaves of orthokeratin.
This report presents an uncommon case of an intraosseous epidermoid cyst occurring without a history of maxillary trauma. Although intraosseous epidermoid cysts are extremely rare in jaws, they should be considered in the differential diagnosis of radiolucent lesions.
表皮样囊肿是一种发生于全身的良性病变。其在口腔内的发生极为罕见。颌骨内表皮样囊肿更为罕见,且难以与其他病变相鉴别。因此,我们希望通过所呈现的临床病例,引起从业者对这种病理情况作为鉴别诊断的关注。
本研究报告了一例无牙上颌骨中一种特殊类型表皮样囊肿的罕见病例。一名70岁男性因上颌前部单一透射区被转诊至保加利亚索非亚“N. I. 皮罗戈夫”大学综合医院积极治疗与急诊医学颌面外科。患者接受了囊肿摘除手术。
基于临床和影像学评估,初步诊断为含牙残余囊肿。苏木精-伊红染色切片的组织病理学检查显示,根据观察到的类似表皮的厚角质层以及衬有多层正角化角质束的复层鳞状上皮,确诊为表皮样囊肿。
本报告呈现了一例无上颌骨创伤史的颌骨内表皮样囊肿罕见病例。尽管颌骨内表皮样囊肿极为罕见,但在透射性病变的鉴别诊断中应予以考虑。