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亚临床甲状腺功能减退与心血管并发症风险之间的关系。

Relationship Between Subclinical Hypothyroidism and the Risk of Cardiovascular Complications.

作者信息

Kaushik Aashi, Agrawal Manjusha

机构信息

Obstetrics and Gynaecology, Jawaharlal Nehru Medical College, Datta Meghe Institute of Medical Sciences, Wardha, IND.

出版信息

Cureus. 2023 Jan 12;15(1):e33708. doi: 10.7759/cureus.33708. eCollection 2023 Jan.

Abstract

Subclinical hypothyroidism is characterized by raised thyroid-stimulating hormone levels in the presence of normal free thyroxine levels. When free thyroxine levels are normal and subclinical hypothyroidism is present, thyroid-stimulating hormone levels are elevated. The impact of subclinical hypothyroidism on the cardiovascular system has recently garnered attention because it is known that thyroid hormones impact the heart and its vasculature. There is compelling evidence linking subclinical hypothyroidism to increased cardiac risks, including changes in blood pressure and cholesterol. It is unclear whether subclinical hypothyroidism is associated with a higher risk of cardiovascular illnesses. In addition to discussing the advantages of levothyroxine therapy in delaying the onset of cardiovascular complications, this review makes the connection between subclinical hypothyroidism patients and the risk of cardiovascular complications-related death.

摘要

亚临床甲状腺功能减退症的特征是在游离甲状腺素水平正常的情况下促甲状腺激素水平升高。当游离甲状腺素水平正常且存在亚临床甲状腺功能减退症时,促甲状腺激素水平会升高。亚临床甲状腺功能减退症对心血管系统的影响最近受到了关注,因为已知甲状腺激素会影响心脏及其血管系统。有令人信服的证据表明亚临床甲状腺功能减退症与心脏风险增加有关,包括血压和胆固醇的变化。目前尚不清楚亚临床甲状腺功能减退症是否与心血管疾病的较高风险相关。除了讨论左甲状腺素治疗在延缓心血管并发症发作方面的优势外,本综述还阐述了亚临床甲状腺功能减退症患者与心血管并发症相关死亡风险之间的联系。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7d3/9922092/00953dea70a3/cureus-0015-00000033708-i01.jpg

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