Xiao Yitong, Calixte Dale A, Fry Elizabeth, Tiesenga Frederick
Surgery, Saint James School of Medicine, Chicago, USA.
Clinical Sciences, St George's University School of Medicine, Chicago, USA.
Cureus. 2023 Jan 12;15(1):e33704. doi: 10.7759/cureus.33704. eCollection 2023 Jan.
Ehlers-Danlos syndrome (EDS) is a group of hereditary disorders characterized by fragility of connective tissue. Clinical manifestations of the disorder involve the skin, joints, blood vessels, and other internal organs. We report the case of a 29-year-old female suffering from EDS and mast cell activation syndrome (MCAS). Her history includes multiple orthopedic surgeries leading to the worsening of her symptoms. This was determined to be due to medical implants placed during her multiple procedures predisposing her to severe immunological reactions. This case report emphasizes the importance of meticulous surgical intervention when managing patients with EDS.
埃勒斯-当洛综合征(EDS)是一组以结缔组织脆弱为特征的遗传性疾病。该疾病的临床表现涉及皮肤、关节、血管和其他内脏器官。我们报告了一例患有EDS和肥大细胞活化综合征(MCAS)的29岁女性病例。她的病史包括多次骨科手术,这些手术导致她的症状恶化。经确定,这是由于她在多次手术过程中植入的医疗植入物使她易发生严重的免疫反应。本病例报告强调了在治疗EDS患者时进行细致手术干预的重要性。