学校环境中 COVID-19 感染链分析：基于学校的 rRT-PCR-漱口池测试系统的数据。
Analysis of COVID-19 Infection Chains in a School Setting: Data From a School-Based rRT-PCR-Gargle Pool Test System.
机构信息
Public Health Office, Cham, Germany.
Department of Pediatric Pneumology and Allergy, University Children's Hospital Regensburg (KUNO) at the Hospital St. Hedwig of the Order of St. John and the University of Regensburg, Regensburg, Germany.
出版信息
Disaster Med Public Health Prep. 2023 Feb 15;17:e312. doi: 10.1017/dmp.2022.279.
BACKGROUND
School testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was implemented in some countries to monitor and prevent SARS-CoV-2 transmissions. Here, we analyze infection chains in primary schools and household members of infected students based on systematic real-time reverse-transcriptase polymerase-chain-reaction (rRT-PCR)-gargle pool testing.
METHODS
Students and school staff ( = 4300) of all 38 primary schools in the rural county of Cham, Germany, were tested twice per week with a gargle pool rRT-PCR system from April to July of 2021. Infection chains of all 8 positive cases identified by school testing were followed up.
RESULTS
In total, 8 positive cases were found by gargle pool PCR testing based on 96,764 school tests. While no transmissions occurred in the school setting, 20 of 27 household members of the 8 cases tested positive. The overall attack rate was 74.1% in families.
CONCLUSIONS
No school outbreaks occurred during the study period. All cases but 1 were initially picked up by school testing. No transmission from school to families was observed.
背景
为了监测和预防严重急性呼吸综合征冠状病毒 2 型（SARS-CoV-2）的传播，一些国家在学校开展了 SARS-CoV-2 检测。在此，我们基于系统的实时逆转录酶聚合酶链反应（rRT-PCR）-咽拭子混合检测，分析了受感染学生的小学感染链和家庭成员。
方法
2021 年 4 月至 7 月，德国农村尚姆县的所有 38 所小学的学生和教职员工（=4300 人）每周接受两次咽拭子混合 rRT-PCR 系统检测。对通过学校检测确定的 8 例阳性病例的所有感染链进行了随访。
结果
共通过 96764 次学校检测，用咽拭子 PCR 检测出 8 例阳性病例。虽然在学校环境中没有发生传播，但 8 例病例的 27 名家庭成员中有 20 人检测呈阳性。家庭中的总发病率为 74.1%。
结论
在研究期间未发生学校暴发。所有病例（除 1 例外）均最初通过学校检测发现。未观察到从学校到家庭的传播。
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