双氟尼酸相关死亡病例报告

A diflunisal related fatality: a case report.

作者信息

Levine B, Smyth D F, Caplan Y H

机构信息

Office of the Chief Medical Examiner of Maryland, Baltimore 21201.

出版信息

Forensic Sci Int. 1987 Sep;35(1):45-50. doi: 10.1016/0379-0738(87)90021-1.

DOI:10.1016/0379-0738(87)90021-1

PMID:3679036

Abstract

A case is reported where the death of an individual resulted from the ingestion of diflunisal. Diflunisal was identified by a combination of liquid chromatography, UV spectrophotometry and colorimetry. Diflunisal was quantified in blood (260 mg/l), bile (71 mg/l), kidney (350 mg/kg), liver (400 mg/kg), stomach contents (34 mg) and urine (78 mg/l). No previous literature references discussing diflunisal related fatalities were available.

摘要

据报道，有一例因摄入二氟尼柳导致个体死亡的案例。通过液相色谱法、紫外分光光度法和比色法相结合的方式鉴定出了二氟尼柳。对血液（260毫克/升）、胆汁（71毫克/升）、肾脏（350毫克/千克）、肝脏（400毫克/千克）、胃内容物（34毫克）和尿液（78毫克/升）中的二氟尼柳进行了定量分析。此前没有关于二氟尼柳相关死亡案例的文献参考。