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胸腰段交界性骨折的手术治疗:一种基于证据的算法。

Surgical management of thoracolumbar junction fractures: An evidence-based algorithm.

作者信息

Giotta Lucifero Alice, Bruno Nunzio, Luzzi Sabino

机构信息

Neurosurgery Unit, Department of Clinical-Surgical, Diagnostic and Pediatric Sciences, University of Pavia, Italy.

Department of Brain and Behavioral Sciences, University of Pavia, Italy.

出版信息

World Neurosurg X. 2023 Jan 20;17:100151. doi: 10.1016/j.wnsx.2022.100151. eCollection 2023 Jan.

Abstract

BACKGROUND

The management of thoracolumbar junction (TLJ) fractures, involving the restoring anatomical stability and biomechanics properties, still remains a challenge for neurosurgeons.Despite the high frequency of these injuries, specific treatment guidelines, set on biomechanical properties, have not yet been assumed. The present study is meant to propose an evidence-based treatment algorithm. The primary aim for the protocol validation was the assessment of postoperative neurological recovery. The secondary objectives concerned the evaluation of residual deformity and rate of hardware failure. Technical nuances of surgical approaches and drawbacks were further discussed.

METHODS

Clinical and biomechanical data of patients harboring a single TLJ fracture, surgically managed between 2015 and 2020, were collected. Patients' cohorts were ranked into 4 groups according to Magerl's Type, McCormack Score, Vaccaro PLC point, Canal encroachment, and Farcy Sagittal Index. The outcome measures were the early/late Benzel-Larson Grade and postoperative kyphosis degree to estimate neurological status and residual deformity, respectively.

RESULTS

32 patients were retrieved, 7, 9, 8, and 8 included within group 1, 2, 3, and 4, respectively. Overall neurological outcomes significantly improved for all patients at every follow-up stage (p ​< ​0.0001). Surgeries gained a complete restoration of post-traumatic kyphosis in the entire cohort (p ​< ​0.0001), except for group 4 which experienced a later worsening of residual deformity.

CONCLUSIONS

The choice of the most appropriate surgical approach for TLJ fractures is dictated by morphological and biomechanical characteristics of fracture and the grade of neurological involvement. The proposed surgical management protocol was reliable and effective, although further validations are needed.

摘要

背景

胸腰段交界处(TLJ)骨折的治疗,包括恢复解剖稳定性和生物力学特性,对神经外科医生来说仍然是一个挑战。尽管这些损伤的发生率很高,但基于生物力学特性制定的具体治疗指南尚未形成。本研究旨在提出一种基于证据的治疗算法。方案验证的主要目标是评估术后神经功能恢复情况。次要目标涉及评估残余畸形和内固定失败率。进一步讨论了手术方法的技术细节和缺点。

方法

收集了2015年至2020年间接受手术治疗的单节段TLJ骨折患者的临床和生物力学数据。根据Magerl分型、McCormack评分、Vaccaro PLC评分、椎管侵占和Farcy矢状指数将患者队列分为4组。结果指标分别为早期/晚期Benzel-Larson分级和术后后凸畸形程度,以评估神经状态和残余畸形。

结果

共纳入32例患者,分别有7例、9例、8例和8例纳入第1、2、3和4组。在每个随访阶段,所有患者的总体神经功能结果均有显著改善(p < 0.0001)。除第4组残余畸形后期恶化外,手术使整个队列的创伤后后凸畸形得到完全恢复(p < 0.0001)。

结论

TLJ骨折最合适的手术方法的选择取决于骨折的形态学和生物力学特征以及神经受累程度。尽管需要进一步验证,但所提出的手术管理方案是可靠且有效的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59e5/9923224/b85456b8420c/gr1.jpg

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