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葡萄牙机构养老老年人跌倒者的特征:药剂师干预是否可行?一项初步研究。

Characterisation of institutionalised Portuguese older adult fallers: is there a place for pharmacist intervention? A preliminary study.

作者信息

Ferreira Carina Ramos, Mascarenhas-Melo Filipa, Rodrigues Ana Rita, Lima Maria João Reis, Pinheiro João Páscoa, Chaves Claúdia, Teixeira-Lemos Edite, Bell Victoria

机构信息

Pharmacist, Laboratory of Social Pharmacy and Public Health, Faculty of Pharmacy of the University of Coimbra, University of Coimbra, Coimbra, Portugal.

Pharmacist, PhD, Drug Development and Technology Laboratory, Faculty of Pharmacy of the University of Coimbra, University of Coimbra, Coimbra, Portugal; REQUIMTE/LAQV, Group of Pharmaceutical Technology, Faculty of Pharmacy of the University of Coimbra, University of Coimbra, Coimbra, Portugal.

出版信息

Pharm Pract (Granada). 2022 Oct-Dec;20(4):2717. doi: 10.18549/PharmPract.2022.4.2717. Epub 2022 Oct 6.

Abstract

BACKGROUND

Falls are a major public health issue, given their prevalence and social impact. Older adults living in long-term care facilities (LTCF) are at greater risk of injury resulting from a fall due to multiple factors, such as nutritional, functional/cognitive impairment, postural instability, polypharmacy, and the presence of potentially inappropriate medications (PIMs). Medication management in LTCF is complex and often sub-optimal and might be crucial for falls. Pharmacist intervention is important, since they have a unique knowledge of medication. However, studies mapping the impact of pharmaceutical activities in Portuguese LTC settings are scarce.

OBJECTIVE

This study aims to assess the characteristics of older adult fallers living in LTFCs and examine the relationship between falling and several factors in this population. We also intend to explore the prevalence of PIMs and their relationship with the occurrence of falls.

METHODS

The study was conducted in two long-term care facilities for elderly people, in the central region of Portugal. We included patients aged 65 and older with no reduced mobility or physical weakness and with the ability to understand spoken and written Portuguese. The following information was assessed: sociodemographic characteristics, comorbidities, polypharmacy, fear of falling, functional, nutritional and cognitive status. PIMs were evaluated according to the Beers criteria (2019).

RESULTS

A total of 69 institutionalised older adults, 45 women and 24 men, with a mean age of 83.14 ± 8.87 years were included. The prevalence of falls was 21.74% Out of these, 46.67% (n=7) fell once, 13.33% (n=2) fell twice, and 40% (n=6) fell 3 or more times. Fallers were mainly women, had lower levels of education, were well nourished, had moderate to severe levels of dependence, and displayed moderate cognitive impairment. All adult fallers had a fear of falling. The main comorbidities of this population were related to the cardiovascular system. Polypharmacy was present in every patient, and at least one PIM was identified in 88.41% of the subjects. Fear of falling (FOF) and cognitive impairment (in subjects with 1 to 11 years of education) showed statistically significant associations with the occurrence of falls (p=0.005 and p=0.05, respectively). No significant differences were found between fallers and non-fallers for any other factors.

CONCLUSIONS

This present study is a preliminary contribution to characterise a group of older adult fallers living in Portuguese LTCFs and demonstrated that fear of falling and cognitive impairment are associated with the occurrence of falls in this population. The high prevalence of polypharmacy and PIMs emphasises the need for tailored interventions featuring the collaboration of a pharmacist to optimise medication management in this population.

摘要

背景

鉴于跌倒的普遍性及其社会影响,它是一个重大的公共卫生问题。居住在长期护理机构(LTCF)中的老年人由于多种因素,如营养、功能/认知障碍、姿势不稳、多重用药以及存在潜在不适当药物(PIM),跌倒受伤的风险更高。长期护理机构中的药物管理复杂且往往欠佳,这可能对跌倒至关重要。药剂师的干预很重要,因为他们对药物有独特的知识。然而,关于葡萄牙长期护理环境中药物活动影响的研究很少。

目的

本研究旨在评估居住在长期护理机构中的老年跌倒者的特征,并研究该人群中跌倒与多种因素之间的关系。我们还打算探讨潜在不适当药物的患病率及其与跌倒发生的关系。

方法

该研究在葡萄牙中部地区的两家老年人长期护理机构中进行。我们纳入了65岁及以上、行动能力未减退或身体无虚弱且能够理解葡萄牙语口语和书面语的患者。评估了以下信息:社会人口学特征、合并症、多重用药、跌倒恐惧、功能、营养和认知状态。根据Beers标准(2019年)评估潜在不适当药物。

结果

共纳入69名机构化老年人,其中45名女性和24名男性,平均年龄为83.14±8.87岁。跌倒患病率为21.74%。其中,46.67%(n = 7)跌倒1次,13.33%(n = 2)跌倒2次,40%(n = 6)跌倒3次或更多次。跌倒者主要为女性,教育程度较低,营养状况良好,有中度至重度依赖水平,并表现出中度认知障碍。所有成年跌倒者都有跌倒恐惧。该人群的主要合并症与心血管系统有关。每位患者都存在多重用药情况,88.41%的受试者中至少识别出一种潜在不适当药物。跌倒恐惧(FOF)和认知障碍(在受教育1至11年的受试者中)与跌倒的发生显示出统计学上的显著关联(分别为p = 0.005和p = 0.05)。在任何其他因素方面,跌倒者和非跌倒者之间未发现显著差异。

结论

本研究是对居住在葡萄牙长期护理机构中的一组老年跌倒者特征描述的初步贡献,并表明跌倒恐惧和认知障碍与该人群中跌倒的发生有关。多重用药和潜在不适当药物的高患病率强调了需要有药剂师合作的量身定制的干预措施,以优化该人群的药物管理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5410/9891778/a426af33c5dc/pharmpract-20-2717-g001.jpg

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