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伴有斜坡骨浆细胞瘤的多发性骨髓瘤表现为动眼神经、滑车神经和展神经多发麻痹：诊断难题。

Multiple myeloma with plasmacytoma of the clivus bone presenting with multiple cranial nerve III, IV, and VI palsy: A diagnostic dilemma.

作者信息

Shah Chiranjiwi Prasad, Chamlagain Rajan, Shah Sangam, Paudel Subodh, Sah Sanjit Kumar, Koirala Bipin, Pandit Kamal, Sitaula Sanjeeta, Shrestha Anjan

机构信息

Maharajgunj Medical Campus, Institute of Medicine Tribhuvan University Maharajgunj Nepal.

Tribhuvan University Teaching Hospital Maharajgunj Nepal.

出版信息

Clin Case Rep. 2023 Feb 13;11(2):e6958. doi: 10.1002/ccr3.6958. eCollection 2023 Feb.

DOI:10.1002/ccr3.6958
PMID:36794041
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9923479/
Abstract

Central nervous system (CNS) manifestation with cranial nerve palsy in multiple myeloma (MM) is a rare manifestation. Plasmacytoma originates from the bones of the skull base in 3% patients with MM but rarely develops from the soft tissues of the nasal cavity and paranasal sinuses. Here, we present a case of 68-year-old male patient with multiple myeloma, clivus bone plasmacytoma, and cavernous sinus syndrome.

摘要

多发性骨髓瘤（MM）伴颅神经麻痹的中枢神经系统（CNS）表现是一种罕见的表现。3%的MM患者浆细胞瘤起源于颅底骨，但很少起源于鼻腔和鼻窦的软组织。在此，我们报告一例68岁男性患者，患有多发性骨髓瘤、斜坡骨浆细胞瘤和海绵窦综合征。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58d4/9923479/ee54c04d09f9/CCR3-11-e6958-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58d4/9923479/a34b4716bc56/CCR3-11-e6958-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58d4/9923479/2111ff134a20/CCR3-11-e6958-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58d4/9923479/801fed9c206d/CCR3-11-e6958-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58d4/9923479/6ccc9d74665d/CCR3-11-e6958-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58d4/9923479/ee54c04d09f9/CCR3-11-e6958-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58d4/9923479/a34b4716bc56/CCR3-11-e6958-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58d4/9923479/2111ff134a20/CCR3-11-e6958-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58d4/9923479/801fed9c206d/CCR3-11-e6958-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58d4/9923479/6ccc9d74665d/CCR3-11-e6958-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58d4/9923479/ee54c04d09f9/CCR3-11-e6958-g004.jpg

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Blood Cancer J. 2017 Sep 1;7(9):e600. doi: 10.1038/bcj.2017.83.
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Sellar and clival plasmacytomas: case series of 5 patients with systematic review of 65 published cases.
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