The Emergency Center, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China.
The Second Clinical School, Wuhan University, Wuhan, Hubei, China.
Front Public Health. 2023 Jan 30;11:1091672. doi: 10.3389/fpubh.2023.1091672. eCollection 2023.
Previous studies have explored the correlation between short-term exposure to air pollution and urinary system diseases, but lack of evidence on the correlation between air pollution and urolithiasis.
Daily data of emergency department visits (EDVs), concentrations of six air pollutants (SO, NO, PM, PM, CO, and O) and meteorological variables were collected in Wuhan, China, from 2016 to 2018. And a time-series study was conducted to investigate short-term effects of air pollutants on urolithiasis EDVs. In addition, stratified analyses by season, age and gender were also conducted.
A total of 7,483 urolithiasis EDVs were included during the study period. A 10-μg/m increase of SO, NO, PM, CO, PM, and O corresponded to 15.02% (95% confidence interval [CI]: 1.69%, 30.11%), 1.96% (95% CI: 0.19%, 3.76%), 1.09% (95% CI:-0.24%, 2.43%), 0.14% (95% CI: 0.02%, 0.26%), 0.72% (95% CI: 0.02%, 1.43%), and 1.17% (95% CI: 0.40%, 1.94%) increases in daily urolithiasis EDVs. Significant positive correlations were observed between SO, NO, CO, and O and urolithiasis EDVs. The correlations were mainly among females (especially PM and CO) and younger people (especially SO, NO, and PM) but the effect of CO was more obvious in elders. Furthermore, the effects of SO and CO were stronger in warm seasons, while the effects of NO were stronger in cool seasons.
Our time-series study indicates that short-term exposure to air pollution (especially SO, NO, CO, and O) was positively correlated with EDVs for urolithiasis in Wuhan, China, and the effects varied by season, age and gender.
先前的研究探讨了短期暴露于空气污染与泌尿系统疾病之间的相关性，但缺乏空气污染与尿石症之间相关性的证据。
本研究于 2016 年至 2018 年在中国武汉收集了急诊就诊次数（EDVs）、六种空气污染物（SO、NO、PM、PM、CO 和 O）浓度和气象变量的日数据，并进行了时间序列研究，以调查空气污染物对尿石症 EDVs 的短期影响。此外，还按季节、年龄和性别进行了分层分析。
本研究期间共纳入 7483 例尿石症 EDVs。SO、NO、PM、CO、PM 和 O 浓度每增加 10μg/m，分别对应 EDVs 增加 15.02%（95%置信区间[CI]：1.69%，30.11%）、1.96%（95% CI：0.19%，3.76%）、1.09%（95% CI：-0.24%，2.43%）、0.14%（95% CI：0.02%，0.26%）、0.72%（95% CI：0.02%，1.43%）和 1.17%（95% CI：0.40%，1.94%）。SO、NO、CO 和 O 与尿石症 EDVs 呈显著正相关。这种相关性主要存在于女性（尤其是 PM 和 CO）和年轻人（尤其是 SO、NO 和 PM）中，但 CO 的影响在老年人中更为明显。此外，SO 和 CO 的影响在温暖季节更强，而 NO 的影响在凉爽季节更强。
本时间序列研究表明，短期暴露于空气污染（尤其是 SO、NO、CO 和 O）与中国武汉的尿石症 EDVs 呈正相关，且这种相关性在不同季节、年龄和性别中存在差异。
