1990 年至 2019 年尿石症发病率和伤残调整生命年趋势：2019 年全球疾病负担研究结果。

Trends in the Incidence and DALYs of Urolithiasis From 1990 to 2019: Results From the Global Burden of Disease Study 2019.

机构信息

Clinical Research Service Center, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.

Collaborative Innovation Engineering Technology Research Center of Clinical Medical Big Data Cloud Service in Medical Consortium of West Guangdong Province, Zhanjiang, China.

出版信息

Front Public Health. 2022 Mar 4;10:825541. doi: 10.3389/fpubh.2022.825541. eCollection 2022.

OBJECTIVES

To provide a comprehensive assessment of the estimated burden and trend of urolithiasis at the global, regional, and national levels.

METHODS

The age-standardized rates (ASRs) of the incidence and disability-adjusted life years (DALYs) of urolithiasis from 1990 to 2019 were obtained from the Global Burden of Disease Study 2019 database. Estimated annual percentage changes (EAPCs) were calculated to quantify the temporal trends in urolithiasis burden.

RESULTS

In 2019, the ASRs of the incidence and DALYs were 1,394.03/100,000 and 7.35/100,000, respectively. The ASRs of the incidence and DALYs of urolithiasis decreased from 1990 to 2019 with EAPCs of -0.83 and -1.77, respectively. Males had a higher burden of urolithiasis than females. In 2019, the highest burden of urolithiasis was observed in regions with high-middle sociodemographic index (SDI), particularly in Eastern Europe, Central Asia, and Southeast Asia. The burden of urolithiasis increased in most countries or territories. The burden of urolithiasis and SDI had a non-linear relationship, and the estimated value of urolithiasis burden was the highest when the SDI value was ~0.7.

CONCLUSION

Globally, the ASRs of the incidence and DALYs of urolithiasis decreased from 1990 to 2019, but an increasing trend was observed among many countries. More effective and appropriate medical and health policies are needed to prevent and early intervene in urolithiasis.

目的

全面评估全球、区域和国家层面尿路结石的负担和趋势。

方法

从 2019 年全球疾病负担研究数据库中获取尿路结石发病率和残疾调整生命年（DALYs）的年龄标准化率（ASR）。计算估计年变化百分比（EAPC）以量化尿路结石负担的时间趋势。

结果

2019 年，尿路结石发病率和 DALY 的 ASR 分别为 1394.03/100000 和 7.35/100000。尿路结石发病率和 DALY 的 ASR 从 1990 年到 2019 年呈下降趋势，EAPC 分别为-0.83 和-1.77。男性尿路结石负担高于女性。2019 年，高-中社会人口指数（SDI）地区尿路结石负担最重，特别是东欧、中亚和东南亚。大多数国家或地区的尿路结石负担都在增加。尿路结石负担和 SDI 之间存在非线性关系，当 SDI 值约为 0.7 时，尿路结石负担的估计值最高。