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急诊科中性粒细胞减少性脓毒症成年患者的评估与管理

Assessment and management of adult patients with neutropenic sepsis in the emergency department.

作者信息

Leloch Daniella Elizabeth

机构信息

Medvivo, Chippenham, England.

出版信息

Emerg Nurse. 2023 Sep 5;31(5):22-26. doi: 10.7748/en.2023.e2159. Epub 2023 Feb 16.

DOI:10.7748/en.2023.e2159
PMID:36794510
Abstract

As cancer diagnoses rise, and more treatment options become available, doctors, nurses and allied health professionals will increasingly encounter more patients with acute oncological emergencies in the emergency department (ED). Neutropenia (low levels of neutrophils in the blood) is a common side effect of systemic anti-cancer therapy, particularly chemotherapy, and has a negative effect on patients' immune system, leaving them vulnerable to infection. Patients who develop neutropenia are at increased risk of developing neutropenic sepsis, a potentially life-threatening condition that requires urgent assessment and treatment within an hour of presentation. This article describes the risk factors for and signs and symptoms of neutropenic sepsis and outlines assessment and management of patients who present to the ED with this condition.

摘要

随着癌症诊断数量的增加,以及更多治疗选择的出现,医生、护士和其他医疗卫生专业人员在急诊科(ED)将会越来越多地遇到患有急性肿瘤急症的患者。中性粒细胞减少症(血液中中性粒细胞水平低)是全身抗癌治疗尤其是化疗的常见副作用,对患者的免疫系统有负面影响,使他们易受感染。发生中性粒细胞减少症的患者发生中性粒细胞减少性脓毒症的风险增加,这是一种潜在的危及生命的病症,需要在就诊后一小时内进行紧急评估和治疗。本文描述了中性粒细胞减少性脓毒症的危险因素、体征和症状,并概述了急诊科接诊此类病症患者的评估和管理方法。

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