Faculty of Medicine and Health Sciences, Antwerp University (UA), Universiteitsplein 1, 2610, Wilrijk, Belgium.
Department of Gynaecology and Obstetrics, ASTARC and Global Health Institute GHI Antwerp University (UA), 2610, Wilrijk, Belgium.
Arch Gynecol Obstet. 2023 Jun;307(6):1833-1838. doi: 10.1007/s00404-022-06897-3. Epub 2023 Feb 16.
This study aims to describe the differences in the urethral motion profile (UMP) of primiparous and multiparous women immediately postpartum.
This prospective study recruited 65 women (29 primiparous, 36 multiparous) one-seven days postpartum. The patients underwent a standardised interview and two-dimensional translabial ultrasound (TLUS). To evaluate the UMP, the urethra was manually traced and divided into five segments with six equidistant points. The mobility vector (MV) for each point was calculated as [Formula: see text]. A Shapiro-Wilk test was conducted to test normality. An independent t-test and a Mann-Whitney test were conducted to express differences between the groups. The Pearson correlation coefficient was used to determine the relationships among MVs, parity and confounders. Finally, a univariate generalised linear regression analysis was performed.
MV1-MV4 were found to be normally distributed. A significant difference for all MVs, except for MV5, was demonstrated between parity groups (MV1: t = 3.88 (p < .001), MV2: t = 3.82 (p < .001), MV3: t = 2.65 (p = .012), MV4: t = 2.54 (p = .015), MV6: U = 150.00 (exact sig. two tailed = .012)). A strong-to-very strong mutual correlation was observed between MV1 to MV4. The univariate generalised linear regression showed that parity can predict up to 26% of urethral mobility.
This study shows that multiparous women have significantly higher urethral mobility compared to primiparous women in the first week postpartum, with the most significant effect observed in the proximal urethra.
本研究旨在描述产后即刻初产妇和经产妇的尿道运动曲线（UMP）差异。
本前瞻性研究招募了 65 名产后 1-7 天的患者（初产妇 29 名，经产妇 36 名）。患者接受了标准访谈和二维经会阴超声（TLUS）检查。为了评估 UMP，手动追踪尿道并将其分为 5 个节段，每个节段有 6 个等距点。计算每个点的移动向量（MV）为[公式：见文本]。进行 Shapiro-Wilk 检验以检验正态性。采用独立 t 检验和 Mann-Whitney 检验比较两组间的差异。采用 Pearson 相关系数确定 MV、产次和混杂因素之间的关系。最后进行单变量广义线性回归分析。
MV1-MV4 呈正态分布。所有 MV 中，除 MV5 外，两组间差异均有统计学意义（MV1：t=3.88（p<0.001），MV2：t=3.82（p<0.001），MV3：t=2.65（p=0.012），MV4：t=2.54（p=0.015），MV6：U=150.00（确切双尾 sig. =0.012））。MV1 到 MV4 之间存在强至极强的相互相关性。单变量广义线性回归显示，产次可预测尿道活动度的 26%。
本研究表明，产后第 1 周经产妇的尿道活动度明显高于初产妇，近端尿道的影响最显著。
