Ji Jiachen, Chen Haojie, Yang Bo, Dong Liang, Wang Min, Huang Xiaoqiang
Xi'an Medical University, Xi'an Shaanxi, 710068, P. R. China.
Department of Orthopedics, Honghui Hospital Affiliated to Medicine College of Xi'an Jiaotong University, Xi'an Shaanxi, 710054, P. R. China.
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2023 Feb 15;37(2):162-167. doi: 10.7507/1002-1892.202211004.
To explore the risk factors for osteonecrosis of the femoral head (ONFH) after treatment of femoral neck fractures with femoral neck system (FNS).
Between January 2020 and February 2021, 179 patients (182 hips) with femoral neck fractures treated by FNS fixation were selected for retrospective analysis. There were 96 males and 83 females with an average age of 53.7 years (range, 20-59 years). There were 106 cases of low-energy-induced injury and 73 cases of high-energy-induced injury. The fractures were classified as type Ⅱ in 40 hips, type Ⅲ in 78 hips, and type Ⅳ in 64 hips according to Garden classification standard, and as typeⅠin 23 hips, type Ⅱ in 66 hips, and type Ⅲ in 93 hips according to Pauwels classification standard. There were 21 patients with diabetes. Patients were divided into ONFH group and non-ONFH group according to whether ONFH occurred at last follow-up. The data of the patients were collected, including age, gender, body mass index (BMI), trauma mechanism, bone mineral density, having diabetes or not, Garden classification and Pauwels classification of fractures, fracture reduction quality, femoral head retroversion angle, and removal of internal fixator or not. The above factors were analyzed by univariate analysis, and then multivariate logistic regression analysis was used to identify risk factors.
Total 179 patients (182 hips) were followed up 20-34 months (mean, 26.5 months). Of these, 30 cases (30 hips) developed ONFH at 9-30 months after operation (ONFH group), and the incidence of ONFH was 16.48%. And 149 cases (152 hips) had no ONFH at last follow-up (non-ONFH group). The univariate analysis showed that there were significant differences between groups in bone mineral density, having diabetes or not, Garden classification, femoral head retroversion angle, and fracture reduction quality ( <0.05). The multivariate logistic regression analysis showed that the Garden type Ⅳ fracture, reduction quality of grading Ⅲ, femoral head retroversion angle >15°, complicated with diabetes were the risk factors for ONFH after FNS fixation ( <0.05).
For the patients with Garden type Ⅳ fracture, poor quality of fracture reduction, femoral head retroversion angle >15°, and diabetes, the risk of ONFH after FNS fixation increases.
探讨采用股骨颈系统(FNS)治疗股骨颈骨折后股骨头坏死(ONFH)的危险因素。
选取2020年1月至2021年2月期间采用FNS内固定治疗的179例(182髋)股骨颈骨折患者进行回顾性分析。其中男性96例,女性83例,平均年龄53.7岁(范围20 - 59岁)。低能量损伤106例,高能量损伤73例。根据Garden分型标准,Ⅱ型骨折40髋,Ⅲ型骨折78髋,Ⅳ型骨折64髋;根据Pauwels分型标准,Ⅰ型骨折23髋,Ⅱ型骨折66髋,Ⅲ型骨折93髋。合并糖尿病患者21例。根据末次随访时是否发生ONFH将患者分为ONFH组和非ONFH组。收集患者的年龄、性别、体重指数(BMI)、创伤机制、骨密度、是否患糖尿病、骨折的Garden分型和Pauwels分型、骨折复位质量、股骨头后倾角以及是否取出内固定物等资料。对上述因素进行单因素分析,然后采用多因素logistic回归分析确定危险因素。
179例(182髋)患者均获随访,随访时间20 - 34个月(平均26.5个月)。其中,30例(30髋)术后9 - 30个月发生ONFH(ONFH组),ONFH发生率为16.48%。149例(152髋)末次随访时未发生ONFH(非ONFH组)。单因素分析显示,两组在骨密度、是否患糖尿病、Garden分型、股骨头后倾角及骨折复位质量方面差异有统计学意义(<0.05)。多因素logistic回归分析显示,GardenⅣ型骨折、复位质量Ⅲ级、股骨头后倾角>15°、合并糖尿病是FNS内固定术后发生ONFH的危险因素(<0.05)。
对于GardenⅣ型骨折、骨折复位质量差、股骨头后倾角>15°及合并糖尿病的患者,FNS内固定术后发生ONFH的风险增加。