Costrini R, Barbieri C, Costa G, Bianchi M, Galloro P, Cattani L, Maselli G, Damiani G, Delli Colli G, Innamorati G
Int J Vitam Nutr Res. 1978;48(4):411-7.
Fructose-1,6-diphosphate (FDP) is able to abolish oxytocin induced spastic inertia in rat uterus. The clinical use of FDP is suggested by observation carried out on 30 deliveries with oxytocin induction. The FDP-treated patients (5 g of FDP in 50 ml of water by intravenous infusion) showed a statistically significant decrease of time elapsed between the beginning of uterine inertia and the recovery of uterine contractions (176 +/- 25.4 min) compared to controls (562 +/- 32.5 min).
果糖-1,6-二磷酸（FDP）能够消除催产素诱导的大鼠子宫痉挛性无力。对30例催产素引产的分娩观察提示了FDP的临床应用价值。与对照组（562±32.5分钟）相比，接受FDP治疗的患者（50毫升水中静脉输注5克FDP）在子宫无力开始至子宫收缩恢复之间的时间有统计学意义的显著缩短（176±25.4分钟）。
