Case report: Clinical characteristics of two cases of pneumonia caused with different strains of .

BACKGROUND

With the development of metagenomic sequencing technologies, more and more cases of pneumonia caused with () have been reported. However, it remains unknown about the characteristics of patients with pneumonia caused by different strains of . Here, we shared the clinical characteristics of two cases of pneumonia caused with strains SZ18-2 and SZ15 which were rarely identified in humans.

CASE PRESENTATION

Case 1: A 69-year-old male farmer who fed ducks presented to hospital for cough, diarrhea and lethargy with the temperature of 39.8°C. Case 2: A 48-year-old male worker who slaughtered ducks was transferred to hospital for high fever, cough, myalgia, diarrhea and loss of appetite. Both patients did not take any protective measures (wearing face masks or gloves) while processing ducks. pneumonia was diagnosed by metagenomic next-generation sequencing and polymerase chain reaction. After treatment with doxycycline and azithromycin individually, they recovered well and discharged from hospital. Through OmpA sequencing, two different strains of SZ18-2 and SZ15 were identified in case 1 and case 2, respectively.

CONCLUSIONS

Patients infected with different strains of may own different clinical manifestations. infection should be suspected when pneumonia appears, accompanied by digestive symptoms and multiple organ dysfunction, especially under the exposure of specific birds.