Fahlbusch Hendrik, Ohlmeier Malte, Mau Hans, Ballhause Tobias, Citak Mustafa, Gehrke Thorsten, Korth Moritz
Department of Orthopedic Surgery, Helios ENDO-Klinik Hamburg, Hamburg, Germany.
Department of Trauma and Orthopaedic Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
SAGE Open Med Case Rep. 2023 Feb 12;11:2050313X231154635. doi: 10.1177/2050313X231154635. eCollection 2023.
The treatment of osteoarthritis in patients with phocomelia with total knee arthroplasty is challenging due to the unusual anatomy and severe deformities. The authors present a case of phocomelia caused by thalidomide with end-stage osteoarthritis and grossly medialized patella. The patient was treated with a cemented constrained non-hinged prosthesis and patelloplasty. Six months later, the patient had complete relief of pain and was able to walk without walking assistance. To our knowledge, total knee replacement in a patient with phocomelia caused by thalidomide has not been described in literature.
由于短肢畸形患者解剖结构异常和严重畸形，采用全膝关节置换术治疗骨关节炎具有挑战性。作者报告了一例因沙利度胺导致短肢畸形并伴有终末期骨关节炎和髌骨严重内移的病例。该患者接受了骨水泥固定的限制性非铰链式假体置换和髌骨成形术。六个月后，患者疼痛完全缓解，无需辅助即可行走。据我们所知，文献中尚未描述过对沙利度胺所致短肢畸形患者进行全膝关节置换的情况。
