Wang Chaojun, Chen Weiqiang, Aili Maimaiti, Zhu Lei, Chen Yan
Institute of Education Science, Leshan Normal University, Leshan, China.
Key Laboratory of Beijing for Identification and Safety Evaluation of Chinese Medicine, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.
Front Plant Sci. 2023 Jan 30;14:1131977. doi: 10.3389/fpls.2023.1131977. eCollection 2023.
tRNA-derived small RNAs (tsRNAs) represent a novel category of small non-coding RNAs and serve as a new regulator of gene expression at both transcriptional and post-transcriptional levels. Growing evidence indicates that tsRNAs can be induced by diverse stimuli and regulate stress-responsive target genes, allowing plants to adapt to unfavorable environments. Here, we discuss the latest developments about the biogenesis and classification of tsRNAs and highlight the expression regulation and potential function of tsRNAs in plant biotic and abiotic stress responses. Of note, we also collect useful bioinformatics tools and resources for tsRNAs study in plants. Finally, we propose current limitations and future directions for plant tsRNAs research. These recent discoveries have refined our understanding of whether and how tsRNAs enhance plant stress tolerance.
转运RNA衍生的小RNA（tsRNAs）代表了一类新型的小非编码RNA，并在转录和转录后水平上作为基因表达的新调节因子。越来越多的证据表明，tsRNAs可由多种刺激诱导产生，并调节应激反应靶基因，使植物能够适应不利环境。在此，我们讨论了tsRNAs生物合成和分类的最新进展，并强调了tsRNAs在植物生物和非生物胁迫反应中的表达调控及潜在功能。值得注意的是，我们还收集了用于植物tsRNAs研究的有用生物信息学工具和资源。最后，我们提出了植物tsRNAs研究当前的局限性和未来方向。这些最新发现完善了我们对tsRNAs是否以及如何增强植物胁迫耐受性的理解。
