University of Pennsylvania School of Nursing, Philadelphia, Pennsylvania.
Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, Pennsylvania.
J Clin Sleep Med. 2023 Jun 1;19(6):1121-1132. doi: 10.5664/jcsm.10516.
Chronic noncancer pain (CP) commonly co-occurs with obstructive sleep apnea (OSA) and may contribute to greater symptom burden. The study aims were to (1) characterize CP among veterans with OSA and (2) examine differences in sleepiness (Epworth Sleepiness Scale), insomnia symptoms (Insomnia Severity Index), and quality of life (Short Form Health Survey-20) in veterans with OSA with or without pre-existing CP.
An observational, cross-sectional, study of 111 veterans with newly diagnosed, untreated OSA was conducted. Descriptive statistics characterized the sample and comorbid CP outcomes. Regression analyses were performed to investigate associations between self-reported CP and sleep-related symptoms or quality of life while controlling for potential confounders.
CP was reported by 69.5% (95% confidence interval: 61.8%, 76.2%) of participants. Having CP was associated with increased Epworth Sleepiness Scale (12.7 ± 5.5 vs 10.2 ± 5.2; = .021) and Insomnia Severity Index scores (18.1 ± 6.2 vs 13.7 ± 7.4; = .002), and worse quality of life across all Short Form Health Survey-20 domains.
There is a high prevalence of CP among veterans with OSA and symptom burden is higher in patients with OSA and CP. Future investigations should address symptom response and burden to OSA treatment in comorbid OSA and CP to guide outcome expectancies and residual OSA symptom treatment plans.
Saconi B, Kuna ST, Polomano RC, Compton PA, Keenan BT, Sawyer AM. Chronic pain is common and worsens daytime sleepiness, insomnia, and quality of life in veterans with obstructive sleep apnea. . 2023;19(6):1121-1132.
慢性非癌性疼痛（CP）常与阻塞性睡眠呼吸暂停（OSA）共存，并可能导致更大的症状负担。本研究旨在：（1）描述患有 OSA 的退伍军人中的 CP 特征；（2）检查患有或不伴有预先存在 CP 的 OSA 退伍军人中，嗜睡（Epworth 嗜睡量表）、失眠症状（失眠严重程度指数）和生活质量（健康调查简表-20）的差异。
对 111 名新诊断、未经治疗的 OSA 退伍军人进行了一项观察性、横断面研究。描述性统计分析了样本和共病 CP 结果。回归分析用于调查在控制潜在混杂因素的情况下，自我报告的 CP 与睡眠相关症状或生活质量之间的关联。
69.5%（95%置信区间：61.8%，76.2%）的参与者报告有 CP。患有 CP 与 Epworth 嗜睡量表评分增加（12.7 ± 5.5 比 10.2 ± 5.2； =.021）和失眠严重程度指数评分增加（18.1 ± 6.2 比 13.7 ± 7.4； =.002）相关，且所有健康调查简表-20 领域的生活质量更差。
患有 OSA 的退伍军人中 CP 的患病率很高，并且 OSA 和 CP 并存的患者的症状负担更高。未来的研究应该针对 OSA 治疗中的共病 OSA 和 CP 的症状反应和负担，以指导预后期望和残余 OSA 症状治疗计划。
Saconi B, Kuna ST, Polomano RC, Compton PA, Keenan BT, Sawyer AM. 慢性疼痛在患有阻塞性睡眠呼吸暂停的退伍军人中很常见，并会加重日间嗜睡、失眠和生活质量。. 2023;19(6):1121-1132.
