Department of Medical Nanotechnology, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Pharmaceutical Analysis Research Center & Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran.
Bioanalysis. 2022 Dec;14(23):1509-1524. doi: 10.4155/bio-2022-0209. Epub 2023 Feb 17.
Aptasensors are amazing among many currently formed procedures due to their excellent particularity, selectivity and responsiveness. These biosensors get more popular in combination with gold nanoparticles (AuNPs) to detect chemical and biological molecules. The response of AuNPs by changing color provides a simple explanation of outcomes. The authors review the recent developments in AuNP-based colorimetric aptasensors designed to sense different chemical and biological molecules. They summarize the procedure of AuNP-based detection and the ordinary instances of currently formed AuNP-based colorimetric procedures. Furthermore, their uses for detecting different analytes based on analyte types are given and the present challenges, overview, and positive views for forming new aptasensors are also regarded.
适体传感器因其优异的特异性、选择性和响应性而在目前形成的众多方法中脱颖而出。这些生物传感器与金纳米粒子（AuNPs）结合使用，在检测化学和生物分子方面变得越来越受欢迎。AuNPs 通过改变颜色来响应，为结果提供了简单的解释。作者综述了基于金纳米粒子的比色适体传感器在检测不同化学和生物分子方面的最新进展。他们总结了基于 AuNP 的检测过程以及目前形成的基于 AuNP 的比色方法的常见实例。此外，还根据分析物类型给出了它们用于检测不同分析物的用途，并考虑了形成新适体传感器的当前挑战、概述和积极观点。
