Diaz Rodrigo, Mantel Jack, Ruppenkamp Jill, Cantu Maricruz, Holy Chantal E
DePuy Synthes, Palm Beach Gardens, Florida, USA.
Health Economics & Market Access, DePuy Synthes, Leeds, UK.
Curr Med Res Opin. 2023 Dec;39(12):1575-1583. doi: 10.1080/03007995.2023.2181150. Epub 2023 Mar 3.
To evaluate real-world outcomes of patients receiving ACTIS, a medial collared, triple-tapered (MCTT) hip system vs. other implants, for primary total hip arthroplasty (THA).
Patients with THA between 2016-2021 from Mercy Healthcare Systems-Orthopedics Database were evaluated. The primary outcome was the 2-year revision. Secondary outcomes included operating room (OR) time, length of stay (LOS), and discharge disposition. Fine Stratification and Weighting (FSW) controlled for baseline characteristic differences between ACTIS and other implant groups. Cox proportional regression evaluated the hazard ratio (HR) for revision.
Among 9,225 patients with 10,205 THAs (mean [SD] age 66.8 [11.3] years, 56.0% female), MCTT was implanted in 1,591 hips and other implants in 8,614 hips. The balanced cohort included all 10,205 procedures (54.2% female; age 65.5 [11.3]; 14.1% Elixhauser index ≥5; 84.5% MCTT, 82.2% other since 2018; obesity 43.6% MCTT, 43.0% other). Two-year revision was 0.9% for MCTT and 1.8% for other implants ( = .021). HR for revision MCTT vs. other was 0.53 (95% CI 0.30-0.92; = .023). Mean (SD) OR time was 69.07 (18.93) minutes for MCTT, 83.69 (43.88) for other implants ( < .001). LOS was 1.99 (1.15) days for MCTT, 2.45 (2.91) for other implants ( < .001). MCTT patients were more likely to be discharged home (90.7% vs 33.8%, < .001) and less likely to be discharged to skilled nursing facilities (SNF) (4.2% vs 9.6%, < .001). One-year cost savings per patient with MCTT was projected at $2,342.
MCTT patients had fewer revisions, reduced OR time, shorter LOS, more home and less SNF discharge, leading to cost savings.
评估接受ACTIS(一种内侧带颈、三锥度[MCTT]髋关节系统)的患者与接受其他植入物的患者在初次全髋关节置换术(THA)中的真实世界结局。
对2016年至2021年来自Mercy医疗系统骨科数据库中的THA患者进行评估。主要结局是2年翻修率。次要结局包括手术室(OR)时间、住院时间(LOS)和出院处置情况。精细分层和加权(FSW)控制了ACTIS组与其他植入物组之间的基线特征差异。Cox比例回归评估翻修的风险比(HR)。
在9225例患者的10205例THA中(平均[标准差]年龄66.8[11.3]岁,女性占56.0%),1591髋植入了MCTT,8614髋植入了其他植入物。平衡队列包括所有10205例手术(女性占54.2%;年龄65.5[11.3]岁;14.1%的埃利克斯豪泽指数≥5;自2018年以来,84.5%为MCTT,82.2%为其他;肥胖患者中,MCTT组占43.6%,其他组占43.0%)。MCTT的2年翻修率为0.9%,其他植入物为1.8%(P = 0.021)。MCTT与其他植入物相比的翻修HR为0.53(95%CI 0.30 - 0.92;P = 0.023)。MCTT的平均(标准差)OR时间为69.07(18.93)分钟,其他植入物为83.69(43.88)分钟(P < 0.001)。MCTT的LOS为1.99(1.15)天,其他植入物为2.45(2.91)天(P < 0.001)。MCTT患者更有可能出院回家(90.7%对33.8%,P < 0.001),而被送往专业护理机构(SNF)的可能性较小(4.2%对9.6%,P < 0.001)。预计使用MCTT的患者每人每年可节省成本2342美元。
MCTT患者的翻修次数更少,OR时间缩短,LOS缩短,回家的比例更高,入住SNF的比例更低,从而节省了成本。