Salame Nicole, Brody Harold J
Both authors are affiliated with the Department of Dermatology, Emory University School of Medicine, Atlanta, Georgia.
Dermatol Surg. 2023 Apr 1;49(4):363-367. doi: 10.1097/DSS.0000000000003712. Epub 2023 Feb 14.
Treatment of acne scarring in darker skin types is fraught with challenges. Highly purified liquid injectable silicone (LIS) is effective in the treatment of acne scars, although its use in darker skin types has yet to be evaluated.
Retrospective evaluation of the safety and efficacy of highly purified LIS for the treatment of acne scars in lighter and darker skin types.
A retrospective chart review of patients who received highly purified LIS for acne scars between July 2010 and March 2021.
Two hundred six total treatments in 96 patients, 32.29% ( n = 31) of whom were Fitzpatrick skin type IV ( n = 20, 20.83%) and V ( n = 11, 11.46%), with depressed and both broad-based and shallow acne scarring were reviewed. Mean age was 50.77 years (SD 16.77), and 83% were female. Complications such as granuloma formation, migration, extrusion of silicone, hyperpigmentation, hematoma, or infection were not observed. The average follow-up time was 6.31 years (SD 3.02).
Highly purified LIS is a safe and effective permanent treatment for acne scars in all skin types. Injection of highly purified LIS using small volume microdroplet technique at 6- to 8-week intervals did not yield any complications, including in patients with darker skin types.
深色皮肤类型的痤疮瘢痕治疗充满挑战。高纯度液体注射用硅胶(LIS)对痤疮瘢痕治疗有效,尽管其在深色皮肤类型中的应用尚未得到评估。
回顾性评估高纯度LIS治疗浅色和深色皮肤类型痤疮瘢痕的安全性和有效性。
对2010年7月至2021年3月期间接受高纯度LIS治疗痤疮瘢痕的患者进行回顾性病历审查。
共对96例患者进行了206次治疗,其中32.29%(n = 31)为Fitzpatrick皮肤IV型(n = 20,20.83%)和V型(n = 11,11.46%),伴有凹陷性以及宽基底和浅表性痤疮瘢痕。平均年龄为50.77岁(标准差16.77),83%为女性。未观察到肉芽肿形成、迁移、硅胶挤出、色素沉着、血肿或感染等并发症。平均随访时间为6.31年(标准差3.02)。
高纯度LIS是治疗所有皮肤类型痤疮瘢痕的一种安全有效的永久性治疗方法。采用小体积微滴技术每隔6至8周注射高纯度LIS未产生任何并发症,包括深色皮肤类型的患者。