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铒玻璃激光治疗 IV 至 VI 型皮肤痤疮瘢痕的安全性和有效性。

Safety and efficacy of erbium-doped yttrium aluminum garnet fractionated laser for treatment of acne scars in type IV to VI skin.

机构信息

Department of Dermatology, Multicultural Dermatology Center, Henry Ford Hospital, Detroit, Michigan, USA.

出版信息

Dermatol Surg. 2010 May;36(5):602-9. doi: 10.1111/j.1524-4725.2010.01513.x. Epub 2010 Apr 1.

Abstract

BACKGROUND

Ablative resurfacing lasers are effective for treatment of acne scars, but they have a high risk of complications. Fractional lasers have less severe side effects but more moderate efficacy than ablative devices. Studies were performed in individuals with Fitzpatrick skin type I to VI.

OBJECTIVE

To determine the efficacy and safety of an erbium 1,550-nm fractional laser in the treatment of facial acne scars in Fitzpatrick skin types IV to VI.

METHODS

We conducted a prospective, single-blind, randomized trial in patients with acne scars (n=15), skin type IV to VI, with a 1,550-nm erbium fractionated laser. Patients were divided into two groups; one was treated with 10 mJ and the other with 40 mJ. Five monthly laser sessions were performed. A patient questionnaire was distributed.

RESULTS

There was a significant improvement in the acne scarring and overall appearance (p<.001). No significant difference was found between 10 and 40 mJ. Patients were highly satisfied with their results. Significant postinflammatory hyperpigmentation was seen; pain was significantly higher in darker skin.

CONCLUSIONS

Fractional photothermolysis is effective for the treatment of acne scars, but practition-ers should be aware of the higher incidence of pain and postinflammatory hyperpigmentation in individuals with skin types IV to VI.

摘要

背景

消融性激光对于痤疮疤痕的治疗非常有效,但存在较高的并发症风险。相比于消融性设备,分束激光的副作用较轻,但疗效也较为温和。这些研究都是在 Fitzpatrick 皮肤类型 I 至 VI 的个体中进行的。

目的

评估 1550nm 铒激光在治疗 Fitzpatrick 皮肤类型 IV 至 VI 的面部痤疮疤痕中的疗效和安全性。

方法

我们进行了一项前瞻性、单盲、随机临床试验,共纳入了 15 名患有痤疮疤痕(Fitzpatrick 皮肤类型 IV 至 VI)的患者,使用 1550nm 铒分束激光进行治疗。患者被分为两组,一组接受 10mJ 治疗,另一组接受 40mJ 治疗。共进行 5 次每月一次的激光治疗。我们还分发了一份患者问卷。

结果

痤疮疤痕和整体外观都有显著改善(p<.001)。10mJ 和 40mJ 之间没有显著差异。患者对治疗结果非常满意。有明显的炎症后色素沉着,肤色越深疼痛越明显。

结论

分束光热解对于痤疮疤痕的治疗是有效的,但治疗师应注意到,在皮肤类型 IV 至 VI 的个体中,疼痛和炎症后色素沉着的发生率更高。

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