Department of Dermatology, Multicultural Dermatology Center, Henry Ford Hospital, Detroit, Michigan, USA.
Dermatol Surg. 2010 May;36(5):602-9. doi: 10.1111/j.1524-4725.2010.01513.x. Epub 2010 Apr 1.
Ablative resurfacing lasers are effective for treatment of acne scars, but they have a high risk of complications. Fractional lasers have less severe side effects but more moderate efficacy than ablative devices. Studies were performed in individuals with Fitzpatrick skin type I to VI.
To determine the efficacy and safety of an erbium 1,550-nm fractional laser in the treatment of facial acne scars in Fitzpatrick skin types IV to VI.
We conducted a prospective, single-blind, randomized trial in patients with acne scars (n=15), skin type IV to VI, with a 1,550-nm erbium fractionated laser. Patients were divided into two groups; one was treated with 10 mJ and the other with 40 mJ. Five monthly laser sessions were performed. A patient questionnaire was distributed.
There was a significant improvement in the acne scarring and overall appearance (p<.001). No significant difference was found between 10 and 40 mJ. Patients were highly satisfied with their results. Significant postinflammatory hyperpigmentation was seen; pain was significantly higher in darker skin.
Fractional photothermolysis is effective for the treatment of acne scars, but practition-ers should be aware of the higher incidence of pain and postinflammatory hyperpigmentation in individuals with skin types IV to VI.
消融性激光对于痤疮疤痕的治疗非常有效，但存在较高的并发症风险。相比于消融性设备，分束激光的副作用较轻，但疗效也较为温和。这些研究都是在 Fitzpatrick 皮肤类型 I 至 VI 的个体中进行的。
评估 1550nm 铒激光在治疗 Fitzpatrick 皮肤类型 IV 至 VI 的面部痤疮疤痕中的疗效和安全性。
我们进行了一项前瞻性、单盲、随机临床试验，共纳入了 15 名患有痤疮疤痕（Fitzpatrick 皮肤类型 IV 至 VI）的患者，使用 1550nm 铒分束激光进行治疗。患者被分为两组，一组接受 10mJ 治疗，另一组接受 40mJ 治疗。共进行 5 次每月一次的激光治疗。我们还分发了一份患者问卷。
痤疮疤痕和整体外观都有显著改善（p<.001）。10mJ 和 40mJ 之间没有显著差异。患者对治疗结果非常满意。有明显的炎症后色素沉着，肤色越深疼痛越明显。
分束光热解对于痤疮疤痕的治疗是有效的，但治疗师应注意到，在皮肤类型 IV 至 VI 的个体中，疼痛和炎症后色素沉着的发生率更高。
