Johnston J K, Neely D P, Latterman S A
Department of Clinical Studies, New Bolton Center, University of Pennsylvania, Kennett Square 19348.
J Am Vet Med Assoc. 1987 Oct 15;191(8):971-2.
A 4.5-month-old Standard-bred filly was referred for evaluation of pigmenturia. Initially, the pigmenturia had resolved with the administration of antibiotics, only to recur after their withdrawal. A dark red urine sample contained numerous RBC, WBC, and gram-negative rods (Escherichia coli). Ultrasonography revealed the right kidney to be large, with multiple cystic structures and a dilated renal pelvis and calices. Cystoscopy revealed a large blood clot within the bladder and urine coming from the left ureteral opening. Urine was not observed coming from the right ureter. It was suspected that the primary infection within the urinary tract was coming from the right kidney, with secondary ureteral obstruction and cystitis. Trimethoprim-sulfamethoxazole treatment was initiated. However, acute depression and abdominal pain developed several days later, and the foal died before assistance could be provided. Necropsy revealed a large abscess that had eroded into the right ureter and aorta and had ruptured, resulting in acute blood loss and death. The location and extensive nature of the lesion would have precluded surgical intervention.
一匹4.5月龄的标准bred小母马因色素尿前来就诊。最初，色素尿在使用抗生素后得到缓解，但停药后又复发。一份暗红色尿液样本中含有大量红细胞、白细胞和革兰氏阴性杆菌（大肠杆菌）。超声检查显示右肾肿大，有多个囊性结构以及肾盂和肾盏扩张。膀胱镜检查发现膀胱内有一个大血块，尿液来自左输尿管开口。未观察到尿液从右输尿管流出。怀疑泌尿系统的原发性感染来自右肾，继发输尿管梗阻和膀胱炎。开始使用甲氧苄啶-磺胺甲恶唑进行治疗。然而，几天后出现急性抑郁和腹痛，这匹小马驹在得到救助之前死亡。尸检发现一个大脓肿已侵蚀到右输尿管和主动脉并破裂，导致急性失血和死亡。病变的位置和广泛程度使得手术干预无法进行。
