Department of Cardiovascular Surgery, University of Health Science Antalya Education and Training Hospital, Antalya, Turkey.
Department of Radiology, Atatürk State Hospital, Antalya, Turkey.
Medicine (Baltimore). 2023 Feb 17;102(7):e33008. doi: 10.1097/MD.0000000000033008.
This study aimed to investigate the effects of pharmacomechanical thrombectomy on novel complete blood count parameters in deep venous thrombosis. This retrospective study included 242 patients aged >18 years who were treated for deep venous thrombosis. Patients were grouped as follows: group 1 was accepted as having interventional operations (n = 123) and group 2 was accepted as having only medical advice (n = 119). Routine complete blood count parameters, the neutrophil-to-lymphocyte ratio (NLR), and the platelet-to-lymphocyte ratio (PLR) were compared. There was no difference between the groups in terms of admission hemoglobin, hematocrit, mean platelet volume, NLR and PLR (P = .11, P = .24, P = .55, P = .93, and P = .96, respectively). In the pharmacomechanic thrombectomy group, NLR and PLR were significantly reduced after intervention when compared to the admission values (P < .001 and P < .001, respectively). However, the NLR and PLR values of medically treated patients did not differ significantly from their baseline values (P = .16 and P = .08, respectively). In this study, we effectively removed the thrombus load in blocked proximal veins using pharmacomechanical thrombectomy and observed a significant decrease in NLR and PLR, which are current, inexpensive, and accessible parameters.
本研究旨在探讨血栓清除术对深静脉血栓形成中新的全血细胞计数参数的影响。这项回顾性研究纳入了 242 名年龄>18 岁的深静脉血栓形成患者。患者分为以下两组：组 1 接受介入手术治疗（n=123），组 2 仅接受药物治疗（n=119）。比较了常规全血细胞计数参数、中性粒细胞与淋巴细胞比值（NLR）和血小板与淋巴细胞比值（PLR）。两组在入院时的血红蛋白、血细胞比容、平均血小板体积、NLR 和 PLR 方面无差异（P=.11，P=.24，P=.55，P=.93，P=.96）。在血栓清除术组中，与入院值相比，干预后 NLR 和 PLR 显著降低（P<.001 和 P<.001）。然而，药物治疗组的 NLR 和 PLR 值与基线值相比无显著差异（P=.16 和 P=.08）。在本研究中，我们使用血栓清除术有效地清除了近端阻塞静脉中的血栓负荷，并观察到 NLR 和 PLR 显著下降，这些参数目前既经济又易得。
