Section of Neurosurgery, Department of Surgery, Aga Khan University Hospital, Karachi.
Ziauddin Medical College, Karachi, Pakistan. Correspondence: Muhammad Shahzad Shamim.
J Pak Med Assoc. 2023 Feb;73(2):430-432. doi: 10.47391/JPMA.13-23.
Subependymal giant cell astrocytomas (SEGA) are benign cranial tumours typically found in patients with tuberous sclerosis complex (TSC). Surgical resection has been the standard treatment for SEGA, however, medical management through mTOR inhibitors has now predominantly replaced surgery as the primary treatment modality. Additionally, newer treatment modalities have emerged with the hopes of providing safer methods for treating the tumour such as laser interstitial thermal therapy (LITT). However, very few reports have addressed these newer methods and analysed the results.
室管膜下巨细胞星形细胞瘤（SEGA）是一种良性的颅内肿瘤，通常发生在结节性硬化症（TSC）患者中。手术切除一直是 SEGA 的标准治疗方法，然而，mTOR 抑制剂的药物治疗现在已主要取代手术成为主要的治疗方式。此外，新的治疗方法已经出现，希望为治疗肿瘤提供更安全的方法，如激光间质热疗（LITT）。然而，很少有报告涉及这些新方法并分析其结果。
