School of Chemical Science and Engineering, Tongji University, Siping Road 1239, Shanghai, 200092, China.
School of Chemical Science and Engineering, Tongji University, Siping Road 1239, Shanghai, 200092, China.
Talanta. 2023 May 15;257:124326. doi: 10.1016/j.talanta.2023.124326. Epub 2023 Feb 14.
Zinc is the second most abundant trace element in the human central nervous system, which is closely related to various physiological activities in the human body. Fluoride ion is one of the most harmful elements in drinking water. Excessive intake of F may cause dental fluorosis, renal failure, or DNA damage. Therefore, it is urgent to develop sensors with high sensitivity and selectivity for the detection of Zn and F ions at the same time. In this work, a series of mixed lanthanide metal-organic frameworks (Ln-MOFs) probes are synthesized using a simple method of in situ doping. The luminous color can be finely modulated by changing the molar ratio of Tb and Eu during synthesis. Benefiting from the unique energy transfer modulation mechanism, the probe has the continuous detection capability of zinc ions and fluoride ions. The detection of Zn and F in a real environment shows that the probe has a good practical application prospect. The as-designed sensor at 262 nm excitation can sequentially detect Zn concentrations ranging from 10 to 10 M (LOD = 4.2 nM) and F levels ranging from 10 to 10 M (LOD = 3.6 μM) with high selectivity. Based on different output signals, a simple Boolean logic gate device is constructed to realize intelligent visualization of Zn and F monitoring.
锌是人体中枢神经系统中第二丰富的微量元素，与人体的各种生理活动密切相关。氟离子是饮用水中最有害的元素之一。过量摄入 F 可能会导致氟斑牙、肾衰竭或 DNA 损伤。因此，迫切需要开发同时具有高灵敏度和选择性的传感器来检测 Zn 和 F 离子。在这项工作中，使用原位掺杂的简单方法合成了一系列混合镧系金属-有机骨架（Ln-MOFs）探针。通过在合成过程中改变 Tb 和 Eu 的摩尔比，可以精细调节发光颜色。受益于独特的能量转移调制机制，探针具有连续检测锌离子和氟离子的能力。在真实环境中对 Zn 和 F 的检测表明，该探针具有良好的实际应用前景。在 262nm 激发下设计的传感器可以顺序检测 10 到 10 M（LOD=4.2 nM）范围内的 Zn 浓度和 10 到 10 M（LOD=3.6 μM）范围内的 F 水平，具有高选择性。基于不同的输出信号，构建了一个简单的布尔逻辑门器件，实现了 Zn 和 F 监测的智能可视化。
