Gibson M J, Szypryt E P, Buckley J H, Worthington B S, Mulholland R C
Spinal Research Unit, Harlow Wood Orthopaedic Hospital, Nr Mansfield, Nottinghamshire, England.
J Bone Joint Surg Br. 1987 Nov;69(5):699-703. doi: 10.1302/0301-620X.69B5.3680327.
Magnetic resonance imaging (MRI) was used to compare the appearance of the spine in 20 adolescents with proven symptomatic intervertebral disc herniations with that in 20 asymptomatic patients who acted as controls. Abnormality in the signal from the nucleus pulposus of one or more discs was present in all patients, while only four of the 20 controls had any abnormal signals. In all the patients the symptomatic disc produced an abnormal signal and in most a herniated fragment of the nucleus pulposus was identified. Fifteen of the 20 patients had multiple-disc abnormality: six had three abnormal discs and nine had two. This suggests there was an underlying diathesis in patients who later developed disc herniation.
采用磁共振成像（MRI）对20例已证实有症状的椎间盘突出症青少年患者的脊柱外观与20例无症状对照患者的脊柱外观进行比较。所有患者均存在一个或多个椎间盘髓核信号异常，而20名对照组中只有4人有任何异常信号。所有患者中，有症状的椎间盘均产生异常信号，且大多数患者可识别出髓核突出碎片。20例患者中有15例存在多节段椎间盘异常：6例有3个异常椎间盘，9例有2个异常椎间盘。这表明后来发生椎间盘突出症的患者存在潜在素质。
