Department of Nuclear Medicine, Yongchuan Hospital affiliated of Chongqing Medical University, Chongqing, China.
Curr Med Imaging. 2023;19(12):1472-1475. doi: 10.2174/1573405619666230220140828.
I-131 uptake in the breast could be occasionally observed in differentiated thyroid cancer who received I-131 scintigraphy or therapy. Herein, we report a postpartum patient with papillary thyroid cancer with breast uptake who received I-131 therapy.
A 33-year-old postpartum woman with thyroid cancer received 120mCi(4440MBq) I- 131 therapy 5 weeks after she ceased to breastfeed. The second day after ingestion of I-131, wholebody scintigraphy demonstrated asymmetric and marked uptake in bilateral breasts. The radiation dose of I-131 in the lactating breast would decrease rapidly by reducing the activity of breasts and expressing breast milk with an electric pump once daily.
The sixth day after administration, scintigraphy demonstrated weak uptake in bilateral breasts.
Physiologic I-131 uptake in the breast could occur in a postpartum woman with thyroid cancer who received I-131 therapy. In this patient, we find that the radiation dose of I-131 accumulated in the lactating breast would decrease rapidly through reducing the activity of breasts and expressing breast milk with an electric pump, which may be a better choice for the postpartum patient who was not given lactation-inhibiting medications and had I-131 therapy.
接受碘-131 闪烁扫描或治疗的分化型甲状腺癌患者偶尔会出现乳腺摄取碘-131。在此，我们报告一例产后甲状腺癌伴乳腺摄取碘-131 的患者。
一名 33 岁的产后甲状腺癌患者在停止哺乳 5 周后接受了 120mCi（4440MBq）碘-131 治疗。碘-131 摄入后的第二天，全身闪烁扫描显示双侧乳房呈不对称性和明显摄取。通过每天使用电动泵减少乳房活动和排空乳汁，可以快速降低哺乳期乳房中碘-131 的辐射剂量。
给药后第 6 天，双乳摄取碘-131 明显减少。
接受碘-131 治疗的产后甲状腺癌妇女可能会出现生理性乳腺摄取碘-131。在本例患者中，我们发现通过减少乳房活动和使用电动泵排空乳汁，可以快速降低哺乳期乳房中碘-131 的辐射剂量，对于未使用哺乳期抑制药物且接受碘-131 治疗的产后患者来说，这可能是一种更好的选择。
