Wray Jennifer N, Soucy Zachary P, Daniel Nicholas J, Weinberg Nicholas E, Krauthamer G Michael, Crockett Sarah C, Pollack Catherine C, Storn Johndavid M
The Geisel School of Medicine at Dartmouth College, Hanover, NH.
The Geisel School of Medicine at Dartmouth College, Hanover, NH; Department of Emergency Medicine, Dartmouth-Hitchcock Medical Center, Lebanon, NH.
Wilderness Environ Med. 2023 Jun;34(2):135-142. doi: 10.1016/j.wem.2022.12.005. Epub 2023 Feb 18.
Point-of-care ultrasound (POCUS) is utilized in austere environments because it is lightweight, durable, battery powered, and portable. In austere settings, weight and space constraints are limitations to carrying dedicated ultrasound gel. Few studies have assessed commonly carried liquids as gel alternatives. The study objective was to assess the suitability of common food and personal care products as ultrasound coupling agents compared with that of commercial gel.
A noninferiority study compared 9 products to commercial gel. Each substance was independently tested on 2 subjects by 2 sonographers covering 8 standardized ultrasound windows. Clips were recorded, blinded, and independently graded by 2 ultrasound fellowship-trained physicians on the ability to make clinical decisions and technical details, including contrast, resolution, and artifact. A 20% noninferiority margin was set, which correlates to levels considered to be of reliably sufficient quality by American College of Emergency Physicians' guidelines. The substances included water, soap, shampoo, olive oil, energy gel, maple syrup, hand sanitizer, sunscreen, and lotion.
A total of 300 of 318 (94%) clips met the primary endpoint of adequacy to make a clinical decision. All media, except sunscreen, were noninferior to commercial gel in the ability to make a clinical decision (α=0.05). In terms of secondary outcomes, resolution, artifact, and contrast, all substances were noninferior to commercial gel (α=0.05). The sonographers concluded that all gel alternatives' usability performed similarly to commercial gel, with the exception of energy gel.
Of the 9 substances tested, 8 were noninferior to commercial gels for clinical decisions. Our study indicates that several POCUS gel substitutes are serviceable to produce clinically adequate images.
床边超声(POCUS)在恶劣环境中得到应用,因为它重量轻、耐用、电池供电且便于携带。在恶劣环境中,重量和空间限制是携带专用超声凝胶的限制因素。很少有研究评估过常用液体作为凝胶替代品的情况。本研究的目的是评估常见食品和个人护理产品作为超声耦合剂的适用性,与商业凝胶进行比较。
一项非劣效性研究比较了 9 种产品与商业凝胶的差异。由 2 名超声医师对每个物质进行独立测试,每位医师对 2 名受检者的 8 个标准化超声窗进行检查。记录视频片段,由 2 名经过超声 fellowship培训的医师进行盲法独立评分,评估其进行临床决策和技术细节的能力,包括对比、分辨率和伪影。设定了 20%的非劣效性边界,这与美国急诊医师学院指南中被认为具有可靠充分质量水平相对应。所包含的物质有水、肥皂、洗发水、橄榄油、能量凝胶、枫糖浆、洗手液、防晒霜和乳液。
在满足做出临床决策的充分性这一首要终点方面,总共 318 个视频片段中的 300 个(94%)符合要求。除防晒霜外,所有介质在做出临床决策的能力方面均不逊于商业凝胶(α=0.05)。在分辨率、伪影和对比方面,所有物质均不逊于商业凝胶(α=0.05)。超声医师的结论是,除能量凝胶外,所有替代凝胶的可用性与商业凝胶相似。
在所测试的 9 种物质中,有 8 种在临床决策方面不逊于商业凝胶。我们的研究表明,几种 POCUS 凝胶替代品可以提供临床充分的图像。