Emergency Department, Hospital Universitario de Burgos, Burgos, Spain.
Emergency Department, Hospital de Sant Pau, Barcelona, Spain.
Int J Cardiol. 2023 May 1;378:64-70. doi: 10.1016/j.ijcard.2023.02.031. Epub 2023 Feb 18.
To investigate whether the existence of heart failure units (HFU) and link nurse units (LNU) in the hospital improve short-term outcomes of acute heart failure (AHF) episodes.
Patients with AHF diagnosed in 45 Spanish emergency departments were analysed according to whether the hospital had a complete development of follow-up units (HFU + LNU), partial (HFU or LNU) or none. The outcomes were: 30-day mortality, hospitalization, in-hospital mortality, >7 days admission, and adverse event (death, rehospitalisation, or reconsultation to the emergency department) at 30 days post-discharge. Outcomes were adjusted for baseline and AHF episode characteristics.
19,947 patients were included, median age was 82 years (IQR 76--87), women were 55%. It was 20% of patients attended in hospitals with null development, 28% with partial development and 52% with complete development. Mortality at 30 days was 10.1% (null/partial/complete development: 10.5%/9.5%/10.4%; p=0.880), hospitalization 74.6% (72.7%/72.7%/75.7%; p<0.001), in-hospital mortality 7.4% (7.6%/7.0%/7.5%; p=0.995), prolonged hospitalization 47.4% (51.1%/52.4%/43.5%; p<0.001) and adverse events 30 days post-hospitalization 30.3% (36.2%/28.9%/30.3%; p < 0.001). In the adjusted analysis, hospital with complete development of follow-up units was not associated with mortality, but with increased hospitalization (OR= 1.172; 95%CI 1.069-1.285) and lower prolonged hospitalization (OR = 0.725; 95%CI 0.660-0.797) and adverse events at 30 days post-discharge (OR=0.831; 95%CI 0.755-0.916). Partial development was only associated with decreased post-discharge adverse events (OR= 0.782; 95%CI 0.702-0.871).
The development of follow-up units is not associated with 30-day mortality, but is associated with less prolonged hospitalization and fewer post-discharge adverse events in patients with AHF.
探讨医院是否设立心力衰竭单元(HFU)和联络护士单元(LNU)是否能改善急性心力衰竭(AHF)患者的短期结局。
分析了在西班牙 45 家急诊科诊断为 AHF 的患者,根据医院是否具有完整的随访单元(HFU+LNU)、部分(HFU 或 LNU)或无进行分组。结局为:30 天死亡率、住院、院内死亡率、>7 天住院和出院后 30 天不良事件(死亡、再住院或重新就诊于急诊科)。结局根据基线和 AHF 发作特征进行调整。
共纳入 19947 例患者,中位年龄为 82 岁(IQR 7687),女性占 55%。20%的患者在未设立任何单元的医院就诊,28%在设立部分单元的医院就诊,52%在设立完整单元的医院就诊。30 天死亡率为 10.1%(未设立/部分设立/完全设立:10.5%/9.5%/10.4%;p=0.880),住院率为 74.6%(72.7%/72.7%/75.7%;p<0.001),院内死亡率为 7.4%(7.6%/7.0%/7.5%;p=0.995),延长住院率为 47.4%(51.1%/52.4%/43.5%;p<0.001),出院后 30 天不良事件发生率为 30.3%(36.2%/28.9%/30.3%;p<0.001)。在调整分析中,设立完整随访单元的医院与死亡率无关,但与住院时间延长(OR=1.172;95%CI 1.0691.285)和出院后不良事件发生率降低(OR=0.725;95%CI 0.6600.797)和出院后 30 天不良事件发生率降低(OR=0.831;95%CI 0.7550.916)有关。部分设立单元仅与出院后不良事件发生率降低有关(OR=0.782;95%CI 0.702~0.871)。
随访单元的设立与 30 天死亡率无关,但与 AHF 患者的延长住院时间减少和出院后不良事件减少有关。