Unaizah College of Medicine and Medical Sciences, Qassim University, Saudi Arabia.
Pol Przegl Chir. 2022 Feb 23;95(2):1-8. doi: 10.5604/01.3001.0015.7676.
Necrotizing fasciitis is an uncommon, rapidly progressive, often aggressive bacterial infection that causes extensive necrosis of the subcutaneous tissue and fascia, relatively sparing the muscle and skin tissues. Rapid diagnosis of the disease is mandatory because the delay in initiation of aggressive treatment negatively influences the outcome. Specific clinical signs may not be always present, which makes an accurate and timely diagnosis difficult. Based on the literature, this article presents a review of the historical background, etiology, pathophysiology, clinical findings, diagnostic strategies, treatment and prognosis of the disease.
坏死性筋膜炎是一种罕见的、快速进展的、通常具有侵袭性的细菌性感染,可导致皮下组织和筋膜广泛坏死,相对地肌肉和皮肤组织较少受累。迅速诊断该病是强制性的,因为延迟开始积极治疗会对预后产生负面影响。特定的临床体征可能并不总是存在,这使得准确和及时的诊断变得困难。基于文献,本文回顾了该病的历史背景、病因、病理生理学、临床发现、诊断策略、治疗和预后。