Younis Rania H, Georgaki Maria, Nikitakis Nikolaos G
Department of Oncology and Diagnostic Sciences, School of Dentistry, University of Maryland, 650 West Baltimore Street, 7th floor suite 7257, Baltimore, MD 21201, USA.
Department of Oral Medicine & Pathology and Hospital Dentistry, School of Dentistry, National and Kapodistrian University of Athens, 2 Thivon Street, 115 27, Goudi, Athens, Greece.
Oral Maxillofac Surg Clin North Am. 2023 May;35(2):261-270. doi: 10.1016/j.coms.2022.10.003. Epub 2023 Feb 15.
Plasma cell gingivitis (PCG) is an inflammatory condition that affects the gingival mucosa of the oral cavity. It is characterized by polyclonal dense plasma cell infiltrate in the connective tissue. Lesions do not respond to prophylactic treatment. Etiology is most likely hypersensitivity to certain antigens (eg, toothpastes, oral rinses, chewing gums, spices). Differential diagnosis of PCG includes reactive, granulomatous, and neoplastic lesions. The diagnostic workup is based on patient's history and the clinicopathologic correlation to rule out mimics of PCG. Dermatologic patch test may be indicated in chronic conditions to identify the allergen.
浆细胞性龈炎（PCG）是一种影响口腔牙龈黏膜的炎症性疾病。其特征是结缔组织中有多克隆密集浆细胞浸润。病变对预防性治疗无反应。病因很可能是对某些抗原（如牙膏、漱口水、口香糖、香料）过敏。PCG的鉴别诊断包括反应性、肉芽肿性和肿瘤性病变。诊断检查基于患者病史及临床病理相关性以排除PCG的模仿者。对于慢性病，可能需要进行皮肤斑贴试验以识别过敏原。
