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提供高蛋白食物可减缓老年护理机构居民营养状况的年龄相关衰退:一项整群随机对照试验。

Provision of High Protein Foods Slows the Age-Related Decline in Nutritional Status in Aged Care Residents: A Cluster-Randomised Controlled Trial.

作者信息

Iuliano S, Poon S, Robbins J, Wang X, Bui M, Seeman E

机构信息

Sandra Iuliano, Department of Endocrinology, University of Melbourne / Austin Health, Heidelberg Repatriation Hospital, Waterdale Road, West Heidelberg, Victoria, Australia, 3081, Email:

出版信息

J Nutr Health Aging. 2023;27(2):166-171. doi: 10.1007/s12603-022-1868-7.

Abstract

OBJECTIVES

Malnutrition, particularly protein insufficiency, is common in institutionalised older adults and increases morbidity, mortality, and costs. We aimed to determine whether 12 months supplementation using high-protein foods (milk, cheese, yoghurt) prevents malnutrition in older adults.

DESIGN

Cluster randomised control study.

SETTING

Sixty Australian aged care facilities.

PARTICIPANTS

Older adults living in aged care homes (n=654, mean age 86.7±7.2 years, 72% females). Intervention Facilities randomly allocated to a high-protein (n=30 intervention) or regular (n=30 controls) menu.

MEASUREMENTS

Nutritional status assessed using the Mini Nutrition Assessment (MNA) tool and fasting morning blood samples (n=302) assayed for haemoglobin (Hb) and albumin. Food intake was monitored 3-monthly using visual plate waste assessment. Measurements at baseline and month 12 were analysed using random effects model accounting for clustering (facility), repeated measure and confounders.

RESULTS

Addition of 11g of protein as 1.5 servings of high-protein foods daily preserved nutritional status that deteriorated in controls [MNA screen (-0.68, 95%CI: -1.03, -0.32, p<0.001) and total (-0.90, 95%CI: -1.45, -0.35, p=0.001) scores], resulting in group differences in MNA screen (0.62, 95%CI: 0.17, 1.06, p=0.007) and total (0.81, 95%CI: 0.11, 1.51, p=0.023) scores and group difference in Hb (3.60g/L, 95%CI: 0.18, 7.03, p=0.039), the net result of preservation with intervention (0.19g/L, 95%CI: -2.04, 2.42, p=0.896) and a decline in controls (-3.41g/L, 95%CI: -6.01, -0.82, p=0.010). No group differences were observed for serum albumin.

CONCLUSION

Consumption of high-protein foods is a pragmatic approach to maintaining nutritional status in older adults in aged-care.

摘要

目的

营养不良,尤其是蛋白质不足,在机构养老的老年人中很常见,会增加发病率、死亡率和成本。我们旨在确定使用高蛋白食物(牛奶、奶酪、酸奶)进行12个月的补充是否能预防老年人营养不良。

设计

整群随机对照研究。

地点

60家澳大利亚老年护理机构。

参与者

居住在老年护理院的老年人(n = 654,平均年龄86.7±7.2岁,72%为女性)。干预措施:机构被随机分配到高蛋白(n = 30个干预组)或常规(n = 30个对照组)菜单。

测量指标

使用微型营养评定法(MNA)工具评估营养状况,并对空腹晨血样本(n = 302)进行血红蛋白(Hb)和白蛋白检测。每3个月使用视觉餐盘浪费评估法监测食物摄入量。使用考虑聚类(机构)、重复测量和混杂因素的随机效应模型分析基线和第12个月的测量结果。

结果

每天添加11克蛋白质,即1.5份高蛋白食物,可保持对照组中恶化的营养状况[MNA筛查得分(-0.68,95%置信区间:-1.03,-0.32,p < 0.001)和总分(-0.90,95%置信区间:-1.45,-0.35,p = 0.001)],导致MNA筛查得分(0.62,95%置信区间:0.17,1.06,p = 0.007)和总分(0.81,95%置信区间:0.11,1.51,p = 0.023)存在组间差异,Hb也存在组间差异(3.60g/L,95%置信区间:0.18,7.03,p = 0.039),干预组保持稳定的净结果为(0.19g/L,95%置信区间:-2.04,2.42,p = 0.896),对照组下降(-3.41g/L,95%置信区间:-6.01,-0.82,p = 0.010)。血清白蛋白未观察到组间差异。

结论

食用高蛋白食物是维持老年护理机构中老年人营养状况的一种实用方法。

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