Laboratory, Utena Co., Ltd., #742 Bldg. D, 3-2-1, Sakado, Takatsu, Kawasaki, Kanagawa, 213-0012, Japan.
Department of Dermatology, Juntendo University School of Medicine, 2-1-1 Hongo, Bunkyo, Tokyo, 113-8421, Japan.
Anal Sci. 2023 Jun;39(6):851-856. doi: 10.1007/s44211-023-00285-w. Epub 2023 Feb 18.
High-frequency spectroscopy (HFS) is an analytical method that is sensitive to slight changes in the dielectric properties of materials. Since water has high permittivity, HFS can be used to detect changes in water content in materials. In this study, we employed HFS to measure human skin moisture during a water sorption-desorption test. Skin without any treatment showed a resonance peak at approximately 1150 MHz. Furthermore, the peak shifted to lower frequency immediately after the application of water to the skin and gradually returned to its original frequency as time progressed. The resonance frequency obtained via least-squares fitting showed that the applied water remained in the skin after 240 s from the beginning of the measurement. These results illustrated that HFS measurements can monitor the progression of decreasing moisture content in human skin during a water sorption-desorption test.
高频光谱（HFS）是一种对材料介电特性的微小变化敏感的分析方法。由于水具有高介电常数，因此 HFS 可用于检测材料中含水量的变化。在这项研究中，我们采用 HFS 测量了在水吸附-解吸试验过程中人体皮肤的水分。未经任何处理的皮肤在大约 1150 MHz 处显示出一个共振峰。此外，在将水施加到皮肤上后，峰值立即移至较低的频率，并随着时间的推移逐渐回到原始频率。通过最小二乘法拟合得到的共振频率表明，从测量开始后 240 秒，施加的水仍留在皮肤中。这些结果表明，HFS 测量可以监测水吸附-解吸试验过程中人体皮肤水分含量逐渐减少的过程。
