Karalar Sıla İspir, Erdoğan Derya, Bostanci İlknur Birol, Zenciroğlu Ayşegül
Pediatric Surgery, Dr. Sami Ulus Maternity Child Health and Disease Training and Research Hospital, University of Health Sciences, Beştepe, Beştepeler Mh, Alparslan Türkeş Cd. No:57, Çankaya, 06560, Ankara, Turkey.
Pediatric Immunology and Allergy, Dr. Sami Ulus Maternity Child Health and Disease Training and Research Hospital, University of Health Sciences, Ankara, Turkey.
Pediatr Surg Int. 2023 Feb 18;39(1):134. doi: 10.1007/s00383-023-05416-y.
Pneumothorax is defined as the presence of air between the parietal and visceral leaves of the pleura, resulting in lung collapse. The aim of this study was to evaluate the respiratory functions of these patients when they reach school age and to reveal whether they cause permanent respiratory pathology.
The files of 229 patients who were hospitalised in a neonatal intensive care clinic had received a diagnosis of pneumothorax and had undergone tube thoracostomy were included in a retrospective cohort review. The respiratory functions of participants in the control and patient groups were evaluated using spirometry in a prospective cross-sectional study design.
The study found the rates of pneumothorax to be higher in males, term infants and after caesarean delivery, mortality was 31%. Among patients who underwent spirometry, those with a history of pneumothorax had lower forced expiratory volume at timed intervals of 0.5 to 1.0 (FEV1), forced vital capacity (FVC), FEV1/FVC, peak expiratory flow (PEF) and forced expiratory flow 25-75% (MEF25-75). FEV1/FVC ratio was significantly lower (p < 0.05).
Patients treated for pneumothorax in the neonatal period should be evaluated for obstructive pulmonary diseases during childhood using respiratory function tests.
气胸定义为胸膜壁层和脏层之间存在空气，导致肺萎陷。本研究的目的是评估这些患者达到学龄期时的呼吸功能，并揭示其是否会引起永久性呼吸病理改变。
回顾性队列研究纳入了229例在新生儿重症监护病房住院、被诊断为气胸并接受了胸腔闭式引流术的患者。在一项前瞻性横断面研究设计中，使用肺活量测定法评估对照组和患者组参与者的呼吸功能。
研究发现男性、足月儿及剖宫产术后气胸发生率更高，死亡率为31%。在接受肺活量测定的患者中，有气胸病史的患者在0.5至1.0秒的定时用力呼气量（FEV1）、用力肺活量（FVC）、FEV1/FVC、呼气峰值流速（PEF）和用力呼气流量25%-75%（MEF25-75）较低。FEV1/FVC比值显著更低（p < 0.05）。
新生儿期接受气胸治疗的患者在儿童期应使用呼吸功能测试评估是否患有阻塞性肺部疾病。
