Ji-Xu Antonio, Mansatta Kushal, Bali Radhika, Moezinia Carine J
University College London Centre for Rheumatology and Connective Tissue Diseases, Royal Free London NHS Foundation Trust, London, United Kingdom.
Dermatol Online J. 2022 Oct 15;28(5). doi: 10.5070/D328559246.
Leukocytoclastic vasculitis is a histopathologic term describing a type of small-vessel vasculitis characterized by a predominantly neutrophilic inflammatory infiltrate and nuclear debris. Skin involvement is common and can have a heterogeneous clinical presentation. Herein, we describe a 76-year-old woman with no history of chemotherapy or recent mushroom ingestion that presented with focal areas of flagellate purpura secondary to bacteremia. Histopathology revealed leukocytoclastic vasculitis and her rash resolved after antibiotic treatment. It is important to distinguish flagellate purpura from a similar condition, flagellate erythema, as they have been reported in association with distinct etiological and histopathological features.
白细胞破碎性血管炎是一个组织病理学术语，用于描述一种小血管炎，其特征主要为中性粒细胞炎性浸润和核碎片。皮肤受累很常见，临床表现可能多种多样。在此，我们描述了一名76岁女性，无化疗史或近期食用蘑菇史，因菌血症出现鞭毛虫样紫癜的局部区域。组织病理学显示为白细胞破碎性血管炎，抗生素治疗后皮疹消退。将鞭毛虫样紫癜与类似疾病鞭毛虫样红斑区分开来很重要，因为据报道它们具有不同的病因和组织病理学特征。
