埃塞俄比亚东部迪尔乔拉转诊医院门诊尿路感染患者的抗生素处方实践：一项机构回顾性横断面研究。
Antibiotics prescribing practice among patients with urinary tract infection at outpatient department, the case of Dilchora referral hospital, Eastern Ethiopia: an institutional retrospective cross-sectional study.
作者信息
Sahilu Tamiru, Kano Zenebe
机构信息
Department of Pharmacy, College of Health Science, Assosa University, Assosa, Ethiopia.
School of Pharmacy, College of Medical and Health Science, Haramaya University, Dire Dawa, Ethiopia.
出版信息
J Pharm Policy Pract. 2023 Feb 21;16(1):23. doi: 10.1186/s40545-023-00539-y.
BACKGROUND
Inappropriate prescription of antibiotics is a global public health challenge. Widespread use, misuse, or inappropriate prescribing has resulted in unnecessary expenditure on drugs, raised risk of adverse reactions, the development of antimicrobial resistance, and increment in health care costs. There is a limited practice in rational prescribing of antibiotics in the management of Urinary tract infection (UTI) in Ethiopia.
OBJECTIVE
To assess antibiotic prescribing practice in the treatment of patients with UTI at outpatient department (OPD), Dilchora referral hospital, Eastern Ethiopia.
METHODS
A retrospective cross-sectional study was conducted from January 7 to March 14, 2021. Data were collected from 600 prescription papers using systematic random sampling method. World Health Organization's standardized core prescribing indicators was used.
RESULTS
A total of 600 prescriptions containing antibiotics prescribed for patients with UTIs were observed during the study period. Of these, 415 (69.19%) were females and 210 (35%) were in the age group of 31-44 years. The number of generic drugs and antibiotics prescribed per encounter was 1.60 and 1.28, respectively. The percentage of antibiotics per prescription was found to be 27.83%. About 88.40% of antibiotics were prescribed by generic names. Fluoroquinolones were the most frequently prescribed class of drugs for the treatment of patients with UTIs.
CONCLUSION
The prescribing practice of antibiotics in patients with UTIs was found to be good as the drugs were prescribed in generic name.
背景
抗生素的不恰当处方是一项全球性的公共卫生挑战。广泛使用、滥用或不恰当的处方导致了不必要的药物支出、不良反应风险增加、抗菌药物耐药性的产生以及医疗保健成本的上升。在埃塞俄比亚，尿路感染（UTI）管理中抗生素合理处方的实践有限。
目的
评估埃塞俄比亚东部迪尔乔拉转诊医院门诊部（OPD）治疗UTI患者时的抗生素处方实践。
方法
于2021年1月7日至3月14日进行了一项回顾性横断面研究。采用系统随机抽样方法从600份处方单中收集数据。使用了世界卫生组织的标准化核心处方指标。
结果
在研究期间，共观察到600份为UTI患者开具的含抗生素处方。其中，415名（69.19%）为女性，210名（35%）年龄在31 - 44岁之间。每次就诊开具的通用名药物和抗生素数量分别为1.60种和1.28种。每张处方中抗生素的比例为27.83%。约88.40%的抗生素以通用名开具。氟喹诺酮类是治疗UTI患者最常开具的药物类别。
结论
UTI患者的抗生素处方实践良好，因为药物是以通用名开具的。
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