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Obesity impacts the expression of Alzheimer's disease-related genes: The Framingham Heart Study.
Alzheimers Dement. 2023 Aug;19(8):3496-3505. doi: 10.1002/alz.12954. Epub 2023 Feb 22.
2
Genetic liability to obesity and peptic ulcer disease: a Mendelian randomization study.
BMC Med Genomics. 2022 Oct 4;15(1):209. doi: 10.1186/s12920-022-01366-x.
3
Genetic variation at the CELF1 (CUGBP, elav-like family member 1 gene) locus is genome-wide associated with Alzheimer's disease and obesity.
Am J Med Genet B Neuropsychiatr Genet. 2014 Jun;165B(4):283-93. doi: 10.1002/ajmg.b.32234. Epub 2014 May 1.
5
Associations Between Obesity and Alzheimer's Disease: Multiple Bioinformatic Analyses.
J Alzheimers Dis. 2021;80(1):271-281. doi: 10.3233/JAD-201235.
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Dissecting the genetic relationship between cardiovascular risk factors and Alzheimer's disease.
Acta Neuropathol. 2019 Feb;137(2):209-226. doi: 10.1007/s00401-018-1928-6. Epub 2018 Nov 9.
9
Adiposity, metabolites, and colorectal cancer risk: Mendelian randomization study.
BMC Med. 2020 Dec 17;18(1):396. doi: 10.1186/s12916-020-01855-9.
10
Body Mass Index and Polygenic Risk for Alzheimer's Disease Predict Conversion to Alzheimer's Disease.
J Gerontol A Biol Sci Med Sci. 2021 Jul 13;76(8):1415-1422. doi: 10.1093/gerona/glab117.

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1
The current status, trends, and challenges of Alzheimer's disease and other dementias in Asia (1990-2036).
Front Public Health. 2025 Jun 10;13:1583339. doi: 10.3389/fpubh.2025.1583339. eCollection 2025.
2
The obesity paradox in cognitive decline: Impact of BMI dynamics and APOE genotypes across various cognitive status.
Diabetes Obes Metab. 2025 Jul;27(7):3967-3983. doi: 10.1111/dom.16433. Epub 2025 May 2.
3
Combining GWAS Summary Data and Proteomics Identified Potential Drug Targets in Dementia.
Mol Neurobiol. 2025 Apr 23. doi: 10.1007/s12035-025-04967-6.
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Correlation between obesity and Alzheimers disease and the mechanisms.
Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2024 Jul 28;49(7):1052-1061. doi: 10.11817/j.issn.1672-7347.2024.240025.
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Body Composition and Alzheimer's Disease: A Holistic Review.
Int J Mol Sci. 2024 Sep 4;25(17):9573. doi: 10.3390/ijms25179573.
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Leptin bioavailability and markers of brain atrophy and vascular injury in the middle age.
Alzheimers Dement. 2024 Sep;20(9):5849-5860. doi: 10.1002/alz.13879. Epub 2024 Aug 12.
8
Non-transgenic guinea pig strains exhibit divergent age-related changes in hippocampal mitochondrial respiration.
Acta Physiol (Oxf). 2024 Aug;240(8):e14185. doi: 10.1111/apha.14185. Epub 2024 Jun 11.
9
Aging as a target for the prevention and treatment of Alzheimer's disease.
Front Neurol. 2024 Apr 5;15:1376104. doi: 10.3389/fneur.2024.1376104. eCollection 2024.
10
The role of longevity-related genetic variant interactions as predictors of survival after 85 years of age.
Mech Ageing Dev. 2024 Jun;219:111926. doi: 10.1016/j.mad.2024.111926. Epub 2024 Mar 13.

本文引用的文献

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Hypoxia-Inducible Factor (HIF) in Ischemic Stroke and Neurodegenerative Disease.
Front Cell Dev Biol. 2021 Jul 28;9:703084. doi: 10.3389/fcell.2021.703084. eCollection 2021.
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Differentially Expressed Genes and Enriched Signaling Pathways in the Adipose Tissue of Obese People.
Front Genet. 2021 May 19;12:620740. doi: 10.3389/fgene.2021.620740. eCollection 2021.
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Obesity and Cardiovascular Disease: A Scientific Statement From the American Heart Association.
Circulation. 2021 May 25;143(21):e984-e1010. doi: 10.1161/CIR.0000000000000973. Epub 2021 Apr 22.
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Genome-wide meta-analysis, fine-mapping and integrative prioritization implicate new Alzheimer's disease risk genes.
Nat Genet. 2021 Mar;53(3):392-402. doi: 10.1038/s41588-020-00776-w. Epub 2021 Feb 15.
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ABCA7 and the altered lipidostasis hypothesis of Alzheimer's disease.
Alzheimers Dement. 2021 Feb;17(2):164-174. doi: 10.1002/alz.12220. Epub 2020 Dec 17.
7
Clusterin as a Potential Biomarker of Obesity-Related Alzheimer's Disease Risk.
Biomark Insights. 2020 Oct 12;15:1177271920964108. doi: 10.1177/1177271920964108. eCollection 2020.
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Higher risk of dementia in English older individuals who are overweight or obese.
Int J Epidemiol. 2020 Aug 1;49(4):1353-1365. doi: 10.1093/ije/dyaa099.
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Alzheimer Disease: An Update on Pathobiology and Treatment Strategies.
Cell. 2019 Oct 3;179(2):312-339. doi: 10.1016/j.cell.2019.09.001. Epub 2019 Sep 26.
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Sex differences in the genetic predictors of Alzheimer's pathology.
Brain. 2019 Sep 1;142(9):2581-2589. doi: 10.1093/brain/awz206.

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