Beran M, Stigendal L, Petruson B
Department of Otolaryngology, University of Göteborg, Sweden.
J Laryngol Otol. 1987 Oct;101(10):1020-8. doi: 10.1017/s0022215100103160.
Ninety-one habitual nose-bleeders were screened for haemostatic disorders. 46 screening results in 38 nose-bleeders were outside the normal range. After extended investigation, it was found that 25 (27 per cent) habitual nose-bleeders had haemostatic disorders, all except one in the primary haemostasis. The disorders found could be classified as mild bleeding disorders (MBD) and compared to the estimated frequency of MBD in the population there was an increased incidence of haemostatic disorders in the habitual nose-bleeders. Abnormal vessels in the nasal mucosa were present in 85 per cent of the investigated nose-bleeders, equally distributed between nose-bleeders with and without haemostatic disorders. This indicates that abnormal vessels and haemostatic disorders in habitual nose-bleeders, it is possible to detect previously unknown but clinically important disorders.
对91名习惯性鼻出血患者进行了止血障碍筛查。38名鼻出血患者的46项筛查结果超出正常范围。经过进一步调查，发现25名（27%）习惯性鼻出血患者存在止血障碍，除1例外在原发性止血方面均有问题。所发现的障碍可归类为轻度出血障碍（MBD），与人群中MBD的估计发生率相比，习惯性鼻出血患者中止血障碍的发生率有所增加。85%的被调查鼻出血患者鼻粘膜血管异常，在有和没有止血障碍的鼻出血患者中分布均匀。这表明，在习惯性鼻出血患者中，异常血管和止血障碍可能会检测到以前未知但临床上重要的障碍。
