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评估糖尿病患者的农产品处方计划:血糖控制的纵向分析。

Evaluation of a Produce Prescription Program for Patients With Diabetes: A Longitudinal Analysis of Glycemic Control.

机构信息

Friedman School of Nutrition Science and Policy, Tufts University, Boston, MA.

Department of Public Health and Community Medicine, School of Medicine, Tufts University, Boston, MA.

出版信息

Diabetes Care. 2023 Jun 1;46(6):1169-1176. doi: 10.2337/dc22-1645.

Abstract

OBJECTIVE

Produce prescriptions have shown promise in improving diabetes care, although most studies have used small samples or lacked controls. Our objective was to evaluate the impacts of a produce prescription program on glycemic control for patients with diabetes.

RESEARCH DESIGN AND METHODS

Participants included a nonrandom enrollment of 252 patients with diabetes who received a produce prescription and 534 similar control participants from two clinics in Hartford, Connecticut. The start of the COVID-19 pandemic in March 2020 coincided with program implementation. Produce prescription enrollees received vouchers ($60 per month) for 6 months to purchase produce at grocery retail. Controls received usual care. The primary outcome was change in glycated hemoglobin (HbA1c) between treatment and control at 6 months. Secondary outcomes included 6-month changes in systolic (SBP) and diastolic blood pressure (DBP), BMI, hospitalizations, and emergency department admissions. Longitudinal generalized estimating equation models, weighted with propensity score overlap weights, assessed changes in outcomes over time.

RESULTS

At 6 months, there was no significant difference in change in HbA1c between treatment and control groups, with a difference of 0.13 percentage points (95% CI -0.05, 0.32). No significant difference was observed for change in SBP (3.85 mmHg; -0.12, 7.82), DBP (-0.82 mmHg; -2.42, 0.79), or BMI (-0.22 kg/m2; -1.83, 1.38). Incidence rate ratios for hospitalizations and emergency department visits were 0.54 (0.14, 1.95) and 0.53 (0.06, 4.72), respectively.

CONCLUSIONS

A 6-month produce prescription program for patients with diabetes, implemented during the onset of the COVID-19 pandemic, was not associated with improved glycemic control.

摘要

目的

开具处方已被证明有助于改善糖尿病患者的护理,但大多数研究使用的样本量较小或缺乏对照。我们的目的是评估开具处方计划对糖尿病患者血糖控制的影响。

研究设计和方法

参与者包括来自康涅狄格州哈特福德市的两个诊所的 252 名患有糖尿病的非随机入组患者和 534 名类似的对照参与者。2020 年 3 月 COVID-19 大流行的开始恰逢计划实施之时。开具处方的参与者获得了 6 个月的每月 60 美元的代金券,用于在杂货店购买农产品。对照组接受常规护理。主要结局是治疗和对照组在 6 个月时糖化血红蛋白(HbA1c)的变化。次要结局包括 6 个月时收缩压(SBP)和舒张压(DBP)、BMI、住院和急诊就诊的变化。使用倾向评分重叠权重的纵向广义估计方程模型评估了随时间的变化。

结果

在 6 个月时,治疗组和对照组之间的 HbA1c 变化没有显著差异,差异为 0.13 个百分点(95%CI-0.05,0.32)。SBP(3.85mmHg;-0.12,7.82)、DBP(-0.82mmHg;-2.42,0.79)或 BMI(-0.22kg/m2;-1.83,1.38)的变化无显著差异。住院和急诊就诊的发生率比分别为 0.54(0.14,1.95)和 0.53(0.06,4.72)。

结论

在 COVID-19 大流行开始时实施的为期 6 个月的糖尿病患者农产品处方计划与改善血糖控制无关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9748/10234740/b15c2afff4f5/dc221645F0GA.jpg

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