Department of Plastic Surgery, MD Anderson Cancer Center, University of Texas, 1400 Pressler Street, Houston, TX 77030, USA.
Department of Plastic Surgery, MD Anderson Cancer Center, University of Texas, 1400 Pressler Street, Houston, TX 77030, USA; University of Texas, Houston School of Medicine, Houston, TX, USA.
Clin Plast Surg. 2023 Apr;50(2):249-257. doi: 10.1016/j.cps.2022.12.001.
Breast implant associated anaplastic large cell lymphoma (BIA-ALCL) is an uncommon and emerging malignancy caused by textured breast implants. The most common patient presentation is delayed seromas, other presentations include breast asymmetry, overlying skin rashes, palpable masses, lymphadenopathy, and capsular contracture. Confirmed diagnoses should receive lymphoma oncology consultation, multidisciplinary evaluation, and PET-CT or CT scan evaluation prior to surgical treatment. Disease confined to the capsule is curable in the majority of patients with complete surgical resection. BIA-ALCL is now recognized as one disease among a spectrum of inflammatory mediated malignancies which include implant-associated squamous cell carcinoma and B cell lymphoma.
乳房植入物相关间变性大细胞淋巴瘤（BIA-ALCL）是一种由纹理乳房植入物引起的罕见且新兴的恶性肿瘤。最常见的患者表现为延迟性血清肿，其他表现包括乳房不对称、覆盖皮肤皮疹、可触及的肿块、淋巴结病和包膜挛缩。确诊的患者应在接受手术治疗前接受淋巴瘤肿瘤学咨询、多学科评估以及 PET-CT 或 CT 扫描评估。大多数患者通过完全手术切除可治愈局限于包膜的疾病。BIA-ALCL 现在被认为是一种炎症介导的恶性肿瘤谱中的一种疾病，包括与植入物相关的鳞状细胞癌和 B 细胞淋巴瘤。
