General Surgery Department, Centro Hospitalar do Tâmega e Sousa, Avenida do Hospital Padre Américo 210, 4564-007 Penafiel, Portugal.
Hepato-Pancreato-Biliary Unit, General Surgery Department, Centro Hospitalar do Tâmega e Sousa, Avenida do Hospital Padre Américo 210, 4564-007 Penafiel, Portugal.
Gastroenterol Clin North Am. 2023 Mar;52(1):37-48. doi: 10.1016/j.gtc.2022.12.002. Epub 2022 Dec 13.
An association between acute pancreatitis (AP) and coronavirus disease 2019 (COVID-19) has been proposed but the mechanisms of pancreatic injury of the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) and the implicative role on the development of AP are not yet fully understood. COVID-19 also imposed major challenges on pancreatic cancer management. We conducted an analysis on the mechanisms of pancreatic injury by SARS-CoV-2 and reviewed published case reports of AP attributed to COVID-19. We also examined the pandemic effect on pancreatic cancer diagnosis and management, including pancreatic surgery.
有人提出急性胰腺炎（AP）与 2019 年冠状病毒病（COVID-19）之间存在关联，但严重急性呼吸综合征冠状病毒 2（SARS-CoV-2）引起胰腺损伤的机制以及其对 AP 发展的影响尚不完全清楚。COVID-19 也给胰腺癌的治疗带来了重大挑战。我们分析了 SARS-CoV-2 引起胰腺损伤的机制，并回顾了已发表的与 COVID-19 相关的 AP 病例报告。我们还研究了大流行对胰腺癌诊断和治疗的影响，包括胰腺手术。
