Ziegler J, Gliedman P, Fass D, Beckman M, Neophytides A, Steinfeld A
Division of Radiation Oncology, NYU Medical Center, New York 10016.
J Neurooncol. 1987;5(3):211-5. doi: 10.1007/BF00151224.
Brain metastasis from ovarian carcinoma is a relatively rare phenomenon. At NYU Medical Center five patients were treated for this entity from 1982 to 1985. The stage at presentation ranged from stage I to stage III, and all patients had received or were receiving chemotherapy. Two patients had active disease elsewhere at diagnosis of brain metastasis, but three patients were otherwise NED. Three patients had solitary cerebellar disease, and two patients had multiple lesions. All patients were treated with whole brain radiotherapy to 3,000 cGy, with neurological improvement in three of the five patients. The central nervous system may need special consideration for prophylactic treatment in those patients with ovarian cancer who receive adjuvant chemotherapy.
卵巢癌脑转移是一种相对罕见的现象。1982年至1985年期间，纽约大学医学中心有5例患者接受了针对该病症的治疗。就诊时的分期从I期到III期不等，所有患者均已接受或正在接受化疗。2例患者在脑转移诊断时其他部位有活动性疾病，但另外3例患者在其他方面无疾病证据。3例患者有孤立性小脑疾病，2例患者有多处病灶。所有患者均接受了3000厘戈瑞的全脑放疗，5例患者中有3例神经功能得到改善。对于接受辅助化疗的卵巢癌患者，中枢神经系统可能需要特别考虑进行预防性治疗。
