长跑后膝关节软骨和半月板的超短回波时间磁化传递成像。
Ultrashort echo time magnetization transfer imaging of knee cartilage and meniscus after long-distance running.
机构信息
Department of Radiology, The Fifth Affiliated Hospital of Sun Yat-Sen University, Zhuhai, 519000, China.
Guangdong Provincial Key Laboratory of Biomedical Imaging, The Fifth Affiliated Hospital, Sun Yat-Sen University, Zhuhai, 519000, Guangdong Province, China.
出版信息
Eur Radiol. 2023 Jul;33(7):4842-4854. doi: 10.1007/s00330-023-09462-x. Epub 2023 Feb 23.
OBJECTIVE
To assess the detection of changes in knee cartilage and meniscus of amateur marathon runners before and after long-distance running using a 3D ultrashort echo time MRI sequence with magnetization transfer preparation (UTE-MT).
METHODS
We recruited 23 amateur marathon runners (46 knees) in this prospective cohort study. MRI scans using UTE-MT and UTE-T2* sequences were performed pre-race, 2 days post-race, and 4 weeks post-race. UTE-MT ratio (UTE-MTR) and UTE-T2* were measured for knee cartilage (eight subregions) and meniscus (four subregions). The sequence reproducibility and inter-rater reliability were also investigated.
RESULTS
Both the UTE-MTR and UTE-T2* measurements showed good reproducibility and inter-rater reliability. For most subregions of cartilage and meniscus, the UTE-MTR values decreased 2 days post-race and increased after 4 weeks of rest. Conversely, the UTE-T2* values increased 2 days post-race and decreased after 4 weeks. The UTE-MTR values in lateral tibial plateau, central medial femoral condyle, and medial tibial plateau showed a significant decrease at 2 days post-race compared to the other two time points (p < 0.05). By comparison, no significant UTE-T2* changes were found for any cartilage subregions. For meniscus, the UTE-MTR values in medial posterior horn and lateral posterior horn regions at 2 days post-race were significantly lower than those at pre-race and 4 weeks post-race (p < 0.05). By comparison, only the UTE-T2* values in medial posterior horn showed a significant difference.
CONCLUSIONS
UTE-MTR is a promising method for the detection of dynamic changes in knee cartilage and meniscus after long-distance running.
KEY POINTS
• Long-distance running causes changes in the knee cartilage and meniscus. • UTE-MT monitors dynamic changes of knee cartilage and meniscal non-invasively. • UTE-MT is superior to UTE-T2* in monitoring dynamic changes in knee cartilage and meniscus.
目的
使用带有磁化传递准备（UTE-MT）的三维超短回波时间 MRI 序列评估业余马拉松运动员长跑前后膝关节软骨和半月板的变化。
方法
本前瞻性队列研究共招募 23 名业余马拉松运动员（46 个膝关节）。在比赛前、赛后 2 天和赛后 4 周分别进行 UTE-MT 和 UTE-T2* 序列 MRI 扫描。测量膝关节软骨（8 个亚区）和半月板（4 个亚区）的 UTE-MT 比（UTE-MTR）和 UTE-T2*。还研究了序列的可重复性和观察者间信度。
结果
UTE-MTR 和 UTE-T2* 测量均具有良好的可重复性和观察者间信度。对于大多数软骨和半月板亚区，UTE-MTR 值在赛后 2 天下降，4 周休息后增加。相反，UTE-T2* 值在赛后 2 天增加，4 周后减少。与其他两个时间点相比，外侧胫骨平台、中央内侧股骨髁和内侧胫骨平台的外侧胫骨平台的 UTE-MTR 值在赛后 2 天明显降低（p<0.05）。相比之下，任何软骨亚区的 UTE-T2* 均无明显变化。对于半月板，内侧后角和外侧后角区域的 UTE-MTR 值在赛后 2 天明显低于术前和 4 周后（p<0.05）。相比之下，只有内侧后角的 UTE-T2* 值有显著差异。
结论
UTE-MTR 是一种有前途的方法，可用于检测长跑后膝关节软骨和半月板的动态变化。
关键点
• 长跑会引起膝关节软骨和半月板的变化。• UTE-MT 可无创监测膝关节软骨和半月板的动态变化。• UTE-MTR 比 UTE-T2* 更能监测膝关节软骨和半月板的动态变化。
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