Jansen Shae, Apondi Edith, Ayaya Samuel O, Kim Jiae, McHenry Megan S
Indiana University School of Medicine, Indianapolis, IN, USA.
Academic Model Providing Access to Healthcare, Eldoret, Kenya.
Glob Pediatr Health. 2023 Feb 17;10:2333794X231156045. doi: 10.1177/2333794X231156045. eCollection 2023.
This retrospective study investigated growth outcomes of Kenyan children born to women living with HIV, comparing children who were orphaned maternally, paternally, and totally (both parents deceased) to those who were non-orphaned. We reviewed HIV clinic visits performed in Kenya from January 2011 to August 2016 in children 0 to 4 years of age. Malnutrition was assessed using stunting, underweight status, and wasting (-scores of ≤-2). Descriptive statistics, Chi-square, -tests, multivariable logistic regression, and ANCOVA models were performed. Of 15 027 total children in the study population, 3.5% (n = 520) were orphaned maternally, 8.1% (n = 1222) were orphaned paternally, and 2.2% (n = 336) were orphaned totally. Children who were orphans had higher rates of malnutrition compared to non-orphans ( < .001). Children who were orphaned maternally and totally had lower anthropometric mean scores, presented to clinic later, and were more likely to be living with HIV. Children who are orphaned maternally or totally should be targeted in interventional strategies.
这项回顾性研究调查了感染艾滋病毒的肯尼亚妇女所生孩子的生长发育情况，将母亲、父亲一方或双方（父母均已故）成为孤儿的儿童与非孤儿儿童进行了比较。我们回顾了2011年1月至2016年8月在肯尼亚对0至4岁儿童进行的艾滋病毒门诊就诊情况。通过发育迟缓、体重不足状况和消瘦（Z评分≤-2）来评估营养不良情况。进行了描述性统计、卡方检验、t检验、多变量逻辑回归和协方差分析模型。在研究人群的15027名儿童中，3.5%（n = 520）为母亲一方成为孤儿，8.1%（n = 1222）为父亲一方成为孤儿，2.2%（n = 336）为父母双方均已故成为孤儿。与非孤儿相比，孤儿的营养不良发生率更高（P <.001）。母亲一方或双方成为孤儿的儿童其人体测量平均得分较低，到诊所就诊较晚，且更有可能感染艾滋病毒。在干预策略中应将母亲一方或双方成为孤儿的儿童作为目标对象。
