Laidlaw S A, Sturman J A, Kopple J D
Department of Medicine, Harbor-UCLA Medical Center, Torrance 90509.
J Nutr. 1987 Nov;117(11):1945-9. doi: 10.1093/jn/117.11.1945.
Taurine levels were measured in adult cats consuming casein-based diets supplemented with 0.2, 0.05, 0.02, 0.01 or 0% (wt/wt) taurine or with 0% taurine plus 5.0% L-cystine. Taurine concentrations in plasma, platelets, granulocytes and erythrocytes declined significantly with decreased dietary taurine. In the cats that did not receive the 5.0% cystine supplement, the relationship between dietary taurine intake and plasma and blood cell taurine level was nonlinear. The greatest increment in taurine concentrations occurred between the 0.02 and 0.05% taurine intakes. These findings suggest that the dietary taurine requirement for adult cats may be between 0.02 and 0.05%. Supplementation of the 0% taurine diet with 5.0% L-cystine raised taurine levels above those of the taurine-deficient diets in plasma and all blood cell types. The result of this study therefore suggest a close relationship between dietary taurine intake and blood cell taurine levels in cats. Five percent L-cystine stimulates taurine synthesis in these animals.
对食用以酪蛋白为基础的日粮的成年猫进行牛磺酸水平测定，这些日粮分别补充了0.2%、0.05%、0.02%、0.01%或0%（重量/重量）的牛磺酸，或0%牛磺酸加5.0%的L-胱氨酸。随着日粮中牛磺酸含量的降低，血浆、血小板、粒细胞和红细胞中的牛磺酸浓度显著下降。在未补充5.0%胱氨酸的猫中，日粮牛磺酸摄入量与血浆和血细胞牛磺酸水平之间的关系呈非线性。牛磺酸浓度的最大增幅出现在牛磺酸摄入量为0.02%至0.05%之间。这些发现表明，成年猫的日粮牛磺酸需求量可能在0.02%至0.05%之间。在0%牛磺酸日粮中补充5.0%的L-胱氨酸，可使血浆和所有血细胞类型中的牛磺酸水平高于牛磺酸缺乏日粮。因此，本研究结果表明猫的日粮牛磺酸摄入量与血细胞牛磺酸水平之间存在密切关系。5%的L-胱氨酸可刺激这些动物体内的牛磺酸合成。
